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Biotinidase Enzyme Blood Test

North Carolina rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated July 2026.

Facilitymedian $43 · 10th–90th $13$930%10%10th90th$43Professionalmedian $13 · 10th–90th $11$220%20%40%10th90th$13$5.0$10.0$20.0$50.0$100.0$200.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$13.49
Median
$45.71
Typical High
$85.11
Aetna
Setting
Professional
Modifier
Global
Typical Low
$13.18
Median
$13.49
Typical High
$22.39
Ambetter
Setting
Professional
Modifier
Global
Typical Low
$11.75
Median
$11.75
Typical High
$11.75
BCBS
Setting
Facility
Modifier
Global
Typical Low
$35.48
Median
$72.44
Typical High
$72.44
BCBS
Setting
Professional
Modifier
Global
Typical Low
$7.59
Median
$10.96
Typical High
$15.49
Cigna
Setting
Facility
Modifier
Global
Typical Low
$11.75
Median
$32.36
Typical High
$77.62
Cigna
Setting
Professional
Modifier
Global
Typical Low
$8.71
Median
$11.75
Typical High
$25.70
Medcost
Setting
Professional
Modifier
Global
Typical Low
$14.13
Median
$30.90
Typical High
$102.33
Medcost
Setting
Facility
Modifier
Global
Typical Low
$13.49
Median
$15.14
Typical High
$33.11
Medcost
Setting
Professional
Modifier
Global
Typical Low
$4.37
Median
$4.37
Typical High
$4.79
Oscar Health
Setting
Facility
Modifier
Global
Typical Low
$302.00
Median
$302.00
Typical High
$302.00
United
Setting
Facility
Modifier
Global
Typical Low
$8.91
Median
$21.88
Typical High
$29.51
United
Setting
Professional
Modifier
Global
Typical Low
$8.51
Median
$11.75
Typical High
$23.44
Wellcare
Setting
Facility
Modifier
Global
Typical Low
$93.33
Median
$93.33
Typical High
$93.33