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Biotinidase Enzyme Blood Test

Mississippi rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated October 2026.

How much does Biotinidase Enzyme Blood Test cost?

$24.55

Typical negotiated rate. In Mississippi, October 2026.

Insurers have agreed to pay about $24.55 for this service. The price depends on where it is billed: about $18.20 from a physician practice, and about $28.84 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$18.20$11.48 to $24.55
FacilityA hospital or hospital-owned outpatient department$28.84$28.84 to $28.84

How much rates vary

Facilitymedian $29 · 10th to 90th $17 to $30Professionalmedian $18 · 10th to 90th $8 to $32
$10$20$50facility $29professional $18

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$18.20
Median
$30.20
Typical High
$33.88
Aetna
Setting
Professional
Modifier
None
Typical Low
$13.18
Median
$30.20
Typical High
$33.88
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$6.61
Median
$15.14
Typical High
$16.98
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$2.69
Median
$6.03
Typical High
$6.92
BCBS Mississippi
Setting
Facility
Modifier
None
Typical Low
$28.84
Median
$28.84
Typical High
$28.84
BCBS Mississippi
Setting
Professional
Modifier
None
Typical Low
$24.55
Median
$24.55
Typical High
$24.55
Cigna
Setting
Facility
Modifier
None
Typical Low
$10.96
Median
$17.38
Typical High
$33.88
Cigna
Setting
Professional
Modifier
None
Typical Low
$7.76
Median
$16.60
Typical High
$32.36
United
Setting
Facility
Modifier
None
Typical Low
$15.14
Median
$15.14
Typical High
$20.42
United
Setting
Professional
Modifier
None
Typical Low
$7.24
Median
$11.48
Typical High
$34.67

Where Mississippi sits

The same service costs 18.6 times more in Kansas than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Mississippi· 6th of 51

$24.55

KS $53.70KY $2.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.