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Biotinidase Enzyme Blood Test

Mississippi rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated July 2026.

How much does Biotinidase Enzyme Blood Test cost?

$19.50

Typical negotiated rate. In Mississippi, July 2026.

Insurers have agreed to pay about $19.50 for this service. The price depends on where it is billed: about $19.50 from a physician practice, and about $23.99 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$19.50$13.18 to $30.20
FacilityA hospital or hospital-owned outpatient department$23.99$18.20 to $30.20

How much rates vary

Facilitymedian $24 · 10th to 90th $15 to $30Professionalmedian $19 · 10th to 90th $13 to $34
$10$20$50facility $24professional $19

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$18.20
Median
$26.92
Typical High
$31.62
Aetna
Setting
Professional
Modifier
Global
Typical Low
$12.88
Median
$19.50
Typical High
$33.88
BCBS
Setting
Facility
Modifier
Global
Typical Low
$28.84
Median
$28.84
Typical High
$28.84
BCBS
Setting
Professional
Modifier
Global
Typical Low
$24.55
Median
$24.55
Typical High
$24.55
Cigna
Setting
Facility
Modifier
Global
Typical Low
$11.48
Median
$18.62
Typical High
$33.88
Cigna
Setting
Professional
Modifier
Global
Typical Low
$7.76
Median
$17.78
Typical High
$34.67
United
Setting
Facility
Modifier
Global
Typical Low
$15.14
Median
$16.98
Typical High
$22.91
United
Setting
Professional
Modifier
Global
Typical Low
$7.08
Median
$12.02
Typical High
$34.67

Where Mississippi sits

The same service costs 3.2 times more in Nebraska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Mississippi· 18th of 51

$19.50

NE $39.81DC $12.59

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.