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Biotinidase Enzyme Blood Test

Minnesota rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated July 2026.

Facilitymedian $46 · 10th–90th $17$1230%20%10th90th$46Professionalmedian $17 · 10th–90th $13$260%20%40%10th90th$17$5.0$10.0$20.0$50.0$100.0$200.0$500.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$15.85
Median
$15.85
Typical High
$53.70
Aetna
Setting
Professional
Modifier
Global
Typical Low
$12.88
Median
$15.85
Typical High
$104.71
BCBS
Setting
Facility
Modifier
Global
Typical Low
$16.98
Median
$16.98
Typical High
$69.18
BCBS
Setting
Professional
Modifier
Global
Typical Low
$13.49
Median
$16.98
Typical High
$16.98
Cigna
Setting
Facility
Modifier
Global
Typical Low
$32.36
Median
$57.54
Typical High
$158.49
Cigna
Setting
Professional
Modifier
Global
Typical Low
$19.50
Median
$24.55
Typical High
$33.11
Health Partners
Setting
Facility
Modifier
Global
Typical Low
$37.15
Median
$53.70
Typical High
$123.03
Health Partners
Setting
Professional
Modifier
Global
Typical Low
$19.50
Median
$19.50
Typical High
$32.36
Medica
Setting
Facility
Modifier
Global
Typical Low
$17.38
Median
$33.88
Typical High
$93.33
Medica
Setting
Professional
Modifier
Global
Typical Low
$7.08
Median
$11.75
Typical High
$35.48
United
Setting
Facility
Modifier
Global
Typical Low
$12.59
Median
$19.50
Typical High
$52.48
United
Setting
Professional
Modifier
Global
Typical Low
$7.08
Median
$16.98
Typical High
$37.15