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Biotinidase Enzyme Blood Test

Michigan rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated July 2026.

How much does Biotinidase Enzyme Blood Test cost?

$15.85

Typical negotiated rate. In Michigan, July 2026.

Insurers have agreed to pay about $15.85 for this service. The price depends on where it is billed: about $15.85 from a physician practice, and about $15.85 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$15.85$12.59 to $18.62
FacilityA hospital or hospital-owned outpatient department$15.85$15.85 to $19.95

How much rates vary

Facilitymedian $16 · 10th to 90th $15 to $30Professionalmedian $16 · 10th to 90th $12 to $20
$10$20$50facility $16professional $16

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$15.14
Median
$15.85
Typical High
$29.51
Aetna
Setting
Professional
Modifier
Global
Typical Low
$14.79
Median
$15.85
Typical High
$19.50
BCBS
Setting
Facility
Modifier
Global
Typical Low
$12.59
Median
$19.05
Typical High
$33.88
BCBS
Setting
Professional
Modifier
Global
Typical Low
$12.02
Median
$12.59
Typical High
$12.59
Cigna
Setting
Professional
Modifier
Global
Typical Low
$11.75
Median
$18.62
Typical High
$23.99
Health Alliance Plan
Setting
Facility
Modifier
Global
Typical Low
$15.85
Median
$15.85
Typical High
$46.77
Health Alliance Plan
Setting
Professional
Modifier
Global
Typical Low
$12.88
Median
$18.62
Typical High
$25.70
Priority Health
Setting
Professional
Modifier
Global
Typical Low
$16.98
Median
$19.50
Typical High
$23.99
United
Setting
Facility
Modifier
Global
Typical Low
$10.00
Median
$16.98
Typical High
$16.98
United
Setting
Professional
Modifier
Global
Typical Low
$7.08
Median
$11.48
Typical High
$19.95

Where Michigan sits

The same service costs 3.2 times more in Nebraska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Michigan· 35th of 51

$15.85

NE $39.81DC $12.59

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.