go back

Biotinidase Enzyme Blood Test

Michigan rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated October 2026.

How much does Biotinidase Enzyme Blood Test cost?

$15.85

Typical negotiated rate. In Michigan, October 2026.

Insurers have agreed to pay about $15.85 for this service. The price depends on where it is billed: about $15.85 from a physician practice, and about $15.85 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$15.85$12.59 to $18.62
FacilityA hospital or hospital-owned outpatient department$15.85$15.85 to $21.88

How much rates vary

Facilitymedian $16 · 10th to 90th $13 to $30Professionalmedian $16 · 10th to 90th $11 to $23
$10$20$50facility $16professional $16

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$15.85
Median
$15.85
Typical High
$25.12
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$7.94
Median
$7.94
Typical High
$12.59
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$3.24
Median
$3.24
Typical High
$5.01
Aetna
Setting
Professional
Modifier
None
Typical Low
$14.45
Median
$16.22
Typical High
$19.50
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$7.24
Median
$8.13
Typical High
$8.51
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$2.88
Median
$3.24
Typical High
$3.39
BCBS
Setting
Facility
Modifier
None
Typical Low
$12.59
Median
$17.78
Typical High
$31.62
BCBS
Setting
Professional
Modifier
None
Typical Low
$12.02
Median
$12.59
Typical High
$13.80
Cigna
Setting
Professional
Modifier
None
Typical Low
$10.72
Median
$13.80
Typical High
$23.99
Health Alliance Plan
Setting
Facility
Modifier
None
Typical Low
$15.85
Median
$15.85
Typical High
$51.29
Health Alliance Plan
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$7.94
Median
$7.94
Typical High
$12.59
Health Alliance Plan
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$3.24
Median
$3.24
Typical High
$5.01
Health Alliance Plan
Setting
Professional
Modifier
None
Typical Low
$15.49
Median
$18.62
Typical High
$25.12
Health Alliance Plan
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$7.94
Median
$7.94
Typical High
$7.94
Health Alliance Plan
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$3.24
Median
$3.24
Typical High
$3.24
Priority Health
Setting
Professional
Modifier
None
Typical Low
$10.72
Median
$16.98
Typical High
$21.88
United
Setting
Facility
Modifier
None
Typical Low
$10.00
Median
$15.14
Typical High
$20.42
United
Setting
Professional
Modifier
None
Typical Low
$7.08
Median
$11.48
Typical High
$21.88

Where Michigan sits

The same service costs 18.6 times more in Kansas than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Michigan· 33rd of 51

$15.85

KS $53.70KY $2.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.