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Biotinidase Enzyme Blood Test

Maine rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated October 2026.

How much does Biotinidase Enzyme Blood Test cost?

$13.80

Typical negotiated rate. In Maine, October 2026.

Insurers have agreed to pay about $13.80 for this service. Most negotiated rates run $8.51 to $20.89.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $22 · 10th to 90th $16 to $95Professionalmedian $10 · 10th to 90th $7 to $21
$10$20$50$100facility $22professional $10

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$13.80
Median
$13.80
Typical High
$13.80
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$16.22
Median
$22.39
Typical High
$95.50
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$6.31
Median
$8.32
Typical High
$10.96
Cigna
Setting
Facility
Modifier
None
Typical Low
$14.79
Median
$23.99
Typical High
$38.02
Cigna
Setting
Professional
Modifier
None
Typical Low
$14.13
Median
$16.98
Typical High
$23.99
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$8.71
Median
$10.00
Typical High
$25.70
Martin's Point
Setting
Professional
Modifier
None
Typical Low
$13.80
Median
$13.80
Typical High
$13.80
United
Setting
Professional
Modifier
None
Typical Low
$8.71
Median
$10.00
Typical High
$25.70

Where Maine sits

The same service costs 18.6 times more in Kansas than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maine· 41st of 51

$13.80

KS $53.70KY $2.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.