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Biotinidase Enzyme Blood Test

Kentucky rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated July 2026.

How much does Biotinidase Enzyme Blood Test cost?

$13.49

Typical negotiated rate. In Kentucky, July 2026.

Insurers have agreed to pay about $13.49 for this service. The price depends on where it is billed: about $13.18 from a physician practice, and about $17.38 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$13.18$2.09 to $15.49
FacilityA hospital or hospital-owned outpatient department$17.38$13.80 to $23.44

How much rates vary

Facilitymedian $17 · 10th to 90th $14 to $33Professionalmedian $13 · 10th to 90th $2 to $23
$2$5$10$20$50$100facility $17professional $13

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$13.80
Median
$17.38
Typical High
$32.36
Aetna
Setting
Professional
Modifier
Global
Typical Low
$13.18
Median
$13.80
Typical High
$47.86
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$10.47
Median
$16.98
Typical High
$17.78
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$2.09
Median
$2.09
Typical High
$8.32
CareSource
Setting
Facility
Modifier
Global
Typical Low
$16.98
Median
$20.42
Typical High
$23.44
CareSource
Setting
Professional
Modifier
Global
Typical Low
$16.98
Median
$20.89
Typical High
$33.88
Cigna
Setting
Facility
Modifier
Global
Typical Low
$13.18
Median
$30.90
Typical High
$39.81
Cigna
Setting
Professional
Modifier
Global
Typical Low
$8.51
Median
$109.65
Typical High
$109.65
United
Setting
Facility
Modifier
Global
Typical Low
$7.59
Median
$16.98
Typical High
$52.48
United
Setting
Professional
Modifier
Global
Typical Low
$1.70
Median
$7.08
Typical High
$23.44

Where Kentucky sits

The same service costs 3.2 times more in Nebraska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Kentucky· 49th of 51

$13.49

NE $39.81DC $12.59

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.