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Biotinidase Enzyme Blood Test

Kentucky rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated October 2026.

How much does Biotinidase Enzyme Blood Test cost?

$2.88

Typical negotiated rate. In Kentucky, October 2026.

Insurers have agreed to pay about $2.88 for this service. The price depends on where it is billed: about $2.82 from a physician practice, and about $16.98 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2.82$2.09 to $8.91
FacilityA hospital or hospital-owned outpatient department$16.98$13.80 to $30.90

How much rates vary

Facilitymedian $17 · 10th to 90th $10 to $31Professionalmedian $3 · 10th to 90th $2 to $19
$2$5$10$20$50$100facility $17professional $3

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$2.82
Median
$13.80
Typical High
$20.89
Aetna
Setting
Professional
Modifier
None
Typical Low
$2.82
Median
$14.13
Typical High
$16.98
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$10.47
Median
$16.98
Typical High
$17.78
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$1.74
Median
$2.09
Typical High
$8.32
CareSource
Setting
Facility
Modifier
None
Typical Low
$16.98
Median
$20.42
Typical High
$23.44
CareSource
Setting
Professional
Modifier
None
Typical Low
$16.98
Median
$20.89
Typical High
$33.88
Cigna
Setting
Facility
Modifier
None
Typical Low
$13.18
Median
$30.90
Typical High
$35.48
Cigna
Setting
Professional
Modifier
None
Typical Low
$8.51
Median
$109.65
Typical High
$109.65
United
Setting
Professional
Modifier
None
Typical Low
$1.70
Median
$7.08
Typical High
$20.89
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$1.41
Median
$7.08
Typical High
$8.51
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$0.56
Median
$2.82
Typical High
$3.39

Where Kentucky sits

The same service costs 18.6 times more in Kansas than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Kentucky· 51st of 51

$2.88

KS $53.70KY $2.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.