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Biotinidase Enzyme Blood Test

Kansas rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated October 2026.

How much does Biotinidase Enzyme Blood Test cost?

$53.70

Typical negotiated rate. In Kansas, October 2026.

Insurers have agreed to pay about $53.70 for this service. The price depends on where it is billed: about $16.98 from a physician practice, and about $61.66 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$16.98$10.00 to $34.67
FacilityA hospital or hospital-owned outpatient department$61.66$58.88 to $87.10

How much rates vary

Facilitymedian $62 · 10th to 90th $28 to $91Professionalmedian $17 · 10th to 90th $10 to $35
$10$20$50$100facility $62professional $17

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$6.61
Median
$30.90
Typical High
$53.70
Aetna
Setting
Professional
Modifier
None
Typical Low
$12.59
Median
$16.98
Typical High
$17.78
Ambetter
Setting
Professional
Modifier
None
Typical Low
$10.23
Median
$10.23
Typical High
$10.23
BCBS Kansas
Setting
Facility
Modifier
None
Typical Low
$58.88
Median
$61.66
Typical High
$91.20
BCBS Kansas
Setting
Professional
Modifier
None
Typical Low
$34.67
Median
$34.67
Typical High
$34.67
Cigna
Setting
Facility
Modifier
None
Typical Low
$11.75
Median
$21.88
Typical High
$38.02
Cigna
Setting
Professional
Modifier
None
Typical Low
$10.23
Median
$43.65
Typical High
$69.18
Medica
Setting
Facility
Modifier
None
Typical Low
$15.14
Median
$27.54
Typical High
$45.71
Medica
Setting
Professional
Modifier
None
Typical Low
$7.08
Median
$10.00
Typical High
$31.62
United
Setting
Facility
Modifier
None
Typical Low
$10.00
Median
$10.00
Typical High
$16.98
United
Setting
Professional
Modifier
None
Typical Low
$7.08
Median
$10.00
Typical High
$35.48
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$7.24
Median
$8.51
Typical High
$8.91
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$2.88
Median
$3.39
Typical High
$3.55

Where Kansas sits

The same service costs 18.6 times more in Kansas than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Kansas· 1st of 51

$53.70

KS $53.70KY $2.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.