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Biotinidase Enzyme Blood Test

Illinois rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated July 2026.

How much does Biotinidase Enzyme Blood Test cost?

$19.50

Typical negotiated rate. In Illinois, July 2026.

Insurers have agreed to pay about $19.50 for this service. The price depends on where it is billed: about $13.49 from a physician practice, and about $33.88 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$13.49$11.75 to $19.50
FacilityA hospital or hospital-owned outpatient department$33.88$21.88 to $39.81

How much rates vary

Facilitymedian $34 · 10th to 90th $14 to $54Professionalmedian $13 · 10th to 90th $3 to $35
$5$10$20$50$100facility $34professional $13

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$13.80
Median
$33.88
Typical High
$45.71
Aetna
Setting
Professional
Modifier
Global
Typical Low
$13.18
Median
$15.14
Typical High
$34.67
BCBS
Setting
Facility
Modifier
Global
Typical Low
$22.91
Median
$45.71
Typical High
$173.78
BCBS
Setting
Professional
Modifier
Global
Typical Low
$3.47
Median
$11.75
Typical High
$12.88
Cigna
Setting
Facility
Modifier
Global
Typical Low
$19.05
Median
$38.90
Typical High
$77.62
Cigna
Setting
Professional
Modifier
Global
Typical Low
$8.91
Median
$19.50
Typical High
$30.90
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$17.78
Median
$29.51
Typical High
$63.10
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$21.88
Median
$21.88
Typical High
$21.88
Molina
Setting
Professional
Modifier
Global
Typical Low
$9.33
Median
$9.33
Typical High
$11.75
United
Setting
Facility
Modifier
Global
Typical Low
$12.59
Median
$16.98
Typical High
$33.88
United
Setting
Professional
Modifier
Global
Typical Low
$7.08
Median
$12.59
Typical High
$20.89

Where Illinois sits

The same service costs 3.2 times more in Nebraska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 24th of 51

$19.50

NE $39.81DC $12.59

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.