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Biotinidase Enzyme Blood Test

Iowa rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated July 2026.

How much does Biotinidase Enzyme Blood Test cost?

$20.42

Typical negotiated rate. In Iowa, July 2026.

Insurers have agreed to pay about $20.42 for this service. The price depends on where it is billed: about $15.85 from a physician practice, and about $44.67 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$15.85$12.88 to $32.36
FacilityA hospital or hospital-owned outpatient department$44.67$24.55 to $214

How much rates vary

Facilitymedian $45 · 10th to 90th $17 to $457Professionalmedian $16 · 10th to 90th $11 to $112
$10$20$50$100$200$500facility $45professional $16

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$12.88
Median
$39.81
Typical High
$91.20
Aetna
Setting
Professional
Modifier
Global
Typical Low
$11.22
Median
$15.85
Typical High
$112.20
Cigna
Setting
Professional
Modifier
Global
Typical Low
$20.89
Median
$32.36
Typical High
$40.74
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$16.98
Median
$29.51
Typical High
$44.67
Medica
Setting
Facility
Modifier
Global
Typical Low
$16.98
Median
$21.88
Typical High
$52.48
Medica
Setting
Professional
Modifier
Global
Typical Low
$10.00
Median
$16.98
Typical High
$43.65
Midlands
Setting
Professional
Modifier
Global
Typical Low
$20.89
Median
$20.89
Typical High
$22.39
Midlands
Setting
Facility
Modifier
Global
Typical Low
$20.89
Median
$20.89
Typical High
$20.89
Oscar Health
Setting
Facility
Modifier
Global
Typical Low
$213.80
Median
$416.87
Typical High
$602.56
United
Setting
Facility
Modifier
Global
Typical Low
$16.98
Median
$16.98
Typical High
$38.90
United
Setting
Professional
Modifier
Global
Typical Low
$10.00
Median
$14.13
Typical High
$42.66
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$13.18
Median
$16.98
Typical High
$16.98

Where Iowa sits

The same service costs 3.2 times more in Nebraska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Iowa· 12th of 51

$20.42

NE $39.81DC $12.59

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.