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Biotinidase Enzyme Blood Test

Georgia rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated October 2026.

How much does Biotinidase Enzyme Blood Test cost?

$14.79

Typical negotiated rate. In Georgia, October 2026.

Insurers have agreed to pay about $14.79 for this service. The price depends on where it is billed: about $11.22 from a physician practice, and about $22.91 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$11.22$8.32 to $25.12
FacilityA hospital or hospital-owned outpatient department$22.91$16.98 to $37.15

How much rates vary

Facilitymedian $23 · 10th to 90th $13 to $59Professionalmedian $11 · 10th to 90th $5 to $33
$10$20$50facility $23professional $11

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$11.22
Median
$11.22
Typical High
$30.90
Aetna
Setting
Professional
Modifier
None
Typical Low
$11.22
Median
$14.45
Typical High
$16.98
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$14.45
Median
$22.39
Typical High
$58.88
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$5.25
Median
$8.91
Typical High
$33.11
CareSource
Setting
Facility
Modifier
None
Typical Low
$11.48
Median
$11.48
Typical High
$11.48
Cigna
Setting
Facility
Modifier
None
Typical Low
$16.98
Median
$37.15
Typical High
$57.54
Cigna
Setting
Professional
Modifier
None
Typical Low
$10.47
Median
$19.50
Typical High
$25.70
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$18.62
Median
$25.70
Typical High
$63.10
United
Setting
Professional
Modifier
None
Typical Low
$7.59
Median
$13.18
Typical High
$35.48
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$5.62
Median
$7.08
Typical High
$8.13
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$2.24
Median
$2.82
Typical High
$3.24

Where Georgia sits

The same service costs 18.6 times more in Kansas than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Georgia· 37th of 51

$14.79

KS $53.70KY $2.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.