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Biotinidase Enzyme Blood Test

Delaware rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated July 2026.

How much does Biotinidase Enzyme Blood Test cost?

$14.13

Typical negotiated rate. In Delaware, July 2026.

Insurers have agreed to pay about $14.13 for this service. Most negotiated rates run $14.13 to $19.50.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 3 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $19 · 10th to 90th $19 to $19Professionalmedian $14 · 10th to 90th $13 to $50
$10$20$50facility $19professional $14

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$19.50
Median
$19.50
Typical High
$19.50
Aetna
Setting
Professional
Modifier
Global
Typical Low
$13.18
Median
$14.13
Typical High
$50.12
Cigna
Setting
Facility
Modifier
Global
Typical Low
$10.96
Median
$10.96
Typical High
$10.96
Cigna
Setting
Professional
Modifier
Global
Typical Low
$10.23
Median
$12.02
Typical High
$31.62
United
Setting
Professional
Modifier
Global
Typical Low
$7.08
Median
$14.13
Typical High
$23.44

Where Delaware sits

The same service costs 3.2 times more in Nebraska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Delaware· 46th of 51

$14.13

NE $39.81DC $12.59

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.