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Biotinidase Enzyme Blood Test

Delaware rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated October 2026.

How much does Biotinidase Enzyme Blood Test cost?

$14.13

Typical negotiated rate. In Delaware, October 2026.

Insurers have agreed to pay about $14.13 for this service. The price depends on where it is billed: about $14.13 from a physician practice, and about $14.13 from a hospital or other facility.

Few insurers publish rates for this combination, so treat this figure as a rough guide.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$14.13$10.00 to $19.50
FacilityA hospital or hospital-owned outpatient department$14.13$10.96 to $30.90

How much rates vary

Facilitymedian $14 · 10th to 90th $11 to $110Professionalmedian $14 · 10th to 90th $7 to $24
$5$10$20$50$100facility $14professional $14

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$14.13
Median
$14.13
Typical High
$14.13
Aetna
Setting
Professional
Modifier
None
Typical Low
$8.91
Median
$14.13
Typical High
$19.50
Cigna
Setting
Facility
Modifier
None
Typical Low
$10.96
Median
$10.96
Typical High
$30.90
Cigna
Setting
Professional
Modifier
None
Typical Low
$10.23
Median
$19.50
Typical High
$109.65
Highmark BCBS
Setting
Facility
Modifier
None
Typical Low
$109.65
Median
$109.65
Typical High
$109.65
United
Setting
Professional
Modifier
None
Typical Low
$4.68
Median
$10.00
Typical High
$23.44

Where Delaware sits

The same service costs 18.6 times more in Kansas than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Delaware· 38th of 51

$14.13

KS $53.70KY $2.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.