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Biotinidase Enzyme Blood Test

Connecticut rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated July 2026.

Facilitymedian $28 · 10th–90th $17$500%10%10th90th$28Professionalmedian $15 · 10th–90th $10$220%20%40%10th90th$15$2.0$5.0$10.0$20.0$50.0$100.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$16.98
Median
$29.51
Typical High
$50.12
Aetna
Setting
Professional
Modifier
Global
Typical Low
$10.72
Median
$15.14
Typical High
$17.78
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$18.20
Median
$26.30
Typical High
$45.71
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$8.32
Median
$11.48
Typical High
$26.30
Cigna
Setting
Facility
Modifier
Global
Typical Low
$11.75
Median
$27.54
Typical High
$67.61
Cigna
Setting
Professional
Modifier
Global
Typical Low
$11.22
Median
$19.50
Typical High
$26.30
ConnectiCare
Setting
Professional
Modifier
Global
Typical Low
$7.94
Median
$16.98
Typical High
$25.12
United
Setting
Facility
Modifier
Global
Typical Low
$16.98
Median
$16.98
Typical High
$16.98
United
Setting
Professional
Modifier
Global
Typical Low
$8.51
Median
$16.98
Typical High
$29.51