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Biotinidase Enzyme Blood Test

Connecticut rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated July 2026.

How much does Biotinidase Enzyme Blood Test cost?

$15.14

Typical negotiated rate. In Connecticut, July 2026.

Insurers have agreed to pay about $15.14 for this service. The price depends on where it is billed: about $15.14 from a physician practice, and about $27.54 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$15.14$11.48 to $15.14
FacilityA hospital or hospital-owned outpatient department$27.54$19.95 to $38.90

How much rates vary

Facilitymedian $28 · 10th to 90th $17 to $50Professionalmedian $15 · 10th to 90th $10 to $22
$10$20$50facility $28professional $15

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$16.98
Median
$29.51
Typical High
$50.12
Aetna
Setting
Professional
Modifier
Global
Typical Low
$10.72
Median
$15.14
Typical High
$17.78
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$18.20
Median
$26.30
Typical High
$45.71
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$8.32
Median
$11.48
Typical High
$26.30
Cigna
Setting
Facility
Modifier
Global
Typical Low
$11.75
Median
$27.54
Typical High
$67.61
Cigna
Setting
Professional
Modifier
Global
Typical Low
$11.22
Median
$19.50
Typical High
$26.30
ConnectiCare
Setting
Professional
Modifier
Global
Typical Low
$7.94
Median
$16.98
Typical High
$25.12
United
Setting
Facility
Modifier
Global
Typical Low
$16.98
Median
$16.98
Typical High
$16.98
United
Setting
Professional
Modifier
Global
Typical Low
$8.51
Median
$16.98
Typical High
$29.51

Where Connecticut sits

The same service costs 3.2 times more in Nebraska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Connecticut· 42nd of 51

$15.14

NE $39.81DC $12.59

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.