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Biotinidase Enzyme Blood Test

Arizona rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated October 2026.

How much does Biotinidase Enzyme Blood Test cost?

$14.13

Typical negotiated rate. In Arizona, October 2026.

Insurers have agreed to pay about $14.13 for this service. The price depends on where it is billed: about $10.00 from a physician practice, and about $33.11 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$10.00$8.91 to $13.18
FacilityA hospital or hospital-owned outpatient department$33.11$16.22 to $50.12

How much rates vary

Facilitymedian $33 · 10th to 90th $11 to $76Professionalmedian $10 · 10th to 90th $7 to $20
$10$20$50$100facility $33professional $10

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$12.88
Median
$53.70
Typical High
$87.10
Aetna
Setting
Professional
Modifier
None
Typical Low
$11.22
Median
$11.22
Typical High
$15.49
BCBS Arizona
Setting
Facility
Modifier
None
Typical Low
$9.55
Median
$42.66
Typical High
$66.07
BCBS Arizona
Setting
Professional
Modifier
None
Typical Low
$8.91
Median
$14.13
Typical High
$20.42
Cigna
Setting
Facility
Modifier
None
Typical Low
$12.02
Median
$33.11
Typical High
$46.77
Cigna
Setting
Professional
Modifier
None
Typical Low
$11.22
Median
$15.14
Typical High
$25.70
Medica
Setting
Facility
Modifier
None
Typical Low
$12.30
Median
$16.98
Typical High
$93.33
Medica
Setting
Professional
Modifier
None
Typical Low
$7.08
Median
$10.00
Typical High
$15.49
United
Setting
Professional
Modifier
None
Typical Low
$7.08
Median
$10.00
Typical High
$23.44
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$5.62
Median
$5.62
Typical High
$5.62
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$2.24
Median
$2.24
Typical High
$2.24

Where Arizona sits

The same service costs 18.6 times more in Kansas than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Arizona· 39th of 51

$14.13

KS $53.70KY $2.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.