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Biotinidase Enzyme Blood Test

Alaska rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated July 2026.

How much does Biotinidase Enzyme Blood Test cost?

$19.50

Typical negotiated rate. In Alaska, July 2026.

Insurers have agreed to pay about $19.50 for this service. The price depends on where it is billed: about $38.02 from a physician practice, and about $15.14 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$38.02$19.50 to $56.23
FacilityA hospital or hospital-owned outpatient department$15.14$15.14 to $25.12

How much rates vary

Facilitymedian $15 · 10th to 90th $15 to $120Professionalmedian $38 · 10th to 90th $17 to $56
$20$50$100$200facility $15professional $38

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$72.44
Median
$131.83
Typical High
$199.53
Aetna
Setting
Professional
Modifier
Global
Typical Low
$19.50
Median
$56.23
Typical High
$112.20
Cigna
Setting
Facility
Modifier
Global
Typical Low
$46.77
Median
$46.77
Typical High
$46.77
Cigna
Setting
Professional
Modifier
Global
Typical Low
$12.30
Median
$19.50
Typical High
$23.99
Moda Health
Setting
Facility
Modifier
Global
Typical Low
$15.14
Median
$15.14
Typical High
$16.98
Moda Health
Setting
Professional
Modifier
Global
Typical Low
$16.98
Median
$16.98
Typical High
$53.70
Premera BCBS
Setting
Facility
Modifier
Global
Typical Low
$58.88
Median
$64.57
Typical High
$109.65
Premera BCBS
Setting
Professional
Modifier
Global
Typical Low
$30.90
Median
$38.02
Typical High
$38.02
Providence
Setting
Facility
Modifier
Global
Typical Low
$15.14
Median
$15.14
Typical High
$15.14
Providence
Setting
Professional
Modifier
Global
Typical Low
$12.30
Median
$16.98
Typical High
$21.88
United
Setting
Facility
Modifier
Global
Typical Low
$52.48
Median
$52.48
Typical High
$52.48
United
Setting
Professional
Modifier
Global
Typical Low
$10.72
Median
$23.44
Typical High
$51.29

Where Alaska sits

The same service costs 3.2 times more in Nebraska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alaska· 20th of 51

$19.50

NE $39.81DC $12.59

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.