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Biotinidase Enzyme Blood Test

Alaska rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated October 2026.

How much does Biotinidase Enzyme Blood Test cost?

$38.02

Typical negotiated rate. In Alaska, October 2026.

Insurers have agreed to pay about $38.02 for this service. The price depends on where it is billed: about $38.02 from a physician practice, and about $64.57 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$38.02$21.88 to $46.77
FacilityA hospital or hospital-owned outpatient department$64.57$46.77 to $117

How much rates vary

Facilitymedian $65 · 10th to 90th $17 to $200Professionalmedian $38 · 10th to 90th $17 to $56
$10$20$50$100$200facility $65professional $38

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$56.23
Median
$117.49
Typical High
$204.17
Aetna
Setting
Professional
Modifier
None
Typical Low
$19.50
Median
$56.23
Typical High
$204.17
Cigna
Setting
Facility
Modifier
None
Typical Low
$46.77
Median
$46.77
Typical High
$46.77
Cigna
Setting
Professional
Modifier
None
Typical Low
$12.30
Median
$19.50
Typical High
$23.99
Moda Health
Setting
Facility
Modifier
None
Typical Low
$15.49
Median
$56.23
Typical High
$199.53
Moda Health
Setting
Professional
Modifier
None
Typical Low
$16.98
Median
$19.50
Typical High
$67.61
Premera BCBS
Setting
Facility
Modifier
None
Typical Low
$58.88
Median
$63.10
Typical High
$109.65
Premera BCBS
Setting
Professional
Modifier
None
Typical Low
$16.98
Median
$38.02
Typical High
$38.02
Providence
Setting
Facility
Modifier
None
Typical Low
$15.49
Median
$46.77
Typical High
$81.28
Providence
Setting
Professional
Modifier
None
Typical Low
$12.30
Median
$16.98
Typical High
$21.88
United
Setting
Professional
Modifier
None
Typical Low
$10.72
Median
$33.88
Typical High
$51.29

Where Alaska sits

The same service costs 18.6 times more in Kansas than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alaska· 2nd of 51

$38.02

KS $53.70KY $2.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.