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Pregnancy Blood Screening For Birth Defects

Missouri rates for HCPCS 81512

Measures five substances in a pregnant woman's blood and combines those results with details such as her age and how far along the pregnancy is. The report gives the chance that the baby has a chromosome difference or an opening in the spine or skull. It is a risk estimate rather than a diagnosis.

Rates data updated October 2026.

How much does Pregnancy Blood Screening For Birth Defects cost?

$58.88

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $58.88 for this service. The price depends on where it is billed: about $44.67 from a physician practice, and about $120 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$44.67$41.69 to $79.43
FacilityA hospital or hospital-owned outpatient department$120$75.86 to $251

How much rates vary

Facilitymedian $120 · 10th to 90th $68 to $331Professionalmedian $45 · 10th to 90th $30 to $100
$50$100$200$500facility $120professional $45

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$58.88
Median
$89.13
Typical High
$128.82
Aetna
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$67.61
Typical High
$69.18
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$69.18
Median
$69.18
Typical High
$323.59
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$27.54
Median
$44.67
Typical High
$125.89
BCBS Kansas City
Setting
Facility
Modifier
None
Typical Low
$95.50
Median
$107.15
Typical High
$190.55
Cigna
Setting
Facility
Modifier
None
Typical Low
$75.86
Median
$154.88
Typical High
$309.03
Cigna
Setting
Professional
Modifier
None
Typical Low
$33.11
Median
$79.43
Typical High
$100.00
Medica
Setting
Facility
Modifier
None
Typical Low
$63.10
Median
$120.23
Typical High
$331.13
Medica
Setting
Professional
Modifier
None
Typical Low
$29.51
Median
$41.69
Typical High
$83.18
United
Setting
Facility
Modifier
None
Typical Low
$63.10
Median
$63.10
Typical High
$63.10
United
Setting
Professional
Modifier
None
Typical Low
$29.51
Median
$41.69
Typical High
$93.33
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$29.51
Median
$30.20
Typical High
$39.81
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$11.75
Median
$12.02
Typical High
$15.85

Where Missouri sits

The same service costs 3.7 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 30th of 51

$58.88

AK $155GA $41.69

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.