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Pregnancy Blood Screening For Birth Defects

Nationwide rates for HCPCS 81512

Measures five substances in a pregnant woman's blood and combines those results with details such as her age and how far along the pregnancy is. The report gives the chance that the baby has a chromosome difference or an opening in the spine or skull. It is a risk estimate rather than a diagnosis.

Rates data updated July 2026.

Facilitymedian $105 · 10th–90th $58$3240%10%20%10th90th$105Professionalmedian $60 · 10th–90th $30$3470%20%10th90th$60$2.0$20.0$200.0$2.0K$20.0K$200.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$109.65
Typical High
$302.00
Aetna
Setting
Professional
Modifier
Global
Typical Low
$48.98
Median
$60.26
Typical High
$346.74
BCBS
Setting
Facility
Modifier
Global
Typical Low
$61.66
Median
$93.33
Typical High
$316.23
BCBS
Setting
Professional
Modifier
Global
Typical Low
$27.54
Median
$30.90
Typical High
$100.00
Cigna
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$134.90
Typical High
$302.00
Cigna
Setting
Professional
Modifier
Global
Typical Low
$37.15
Median
$85.11
Typical High
$165.96
United
Setting
Facility
Modifier
Global
Typical Low
$29.51
Median
$69.18
Typical High
$83.18
United
Setting
Professional
Modifier
Global
Typical Low
$29.51
Median
$41.69
Typical High
$87.10