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Large Multi-Gene Tumor Sequencing Panel

South Dakota rates for HCPCS 81455

This laboratory service analyzes a large panel of genes from a tumor or blood sample to look for genetic changes that can help guide cancer diagnosis and treatment decisions. It examines many genes at once using next-generation sequencing technology, offering a broader look than smaller, more targeted gene panels. Results can help identify mutations that inform prognosis or point toward targeted therapies.

Rates data updated July 2026.

Facilitymedian $5,623 · 10th–90th $2,884$5,6230%50%10th$5,623Professionalmedian $3,388 · 10th–90th $1,950$7,0790%10%10th90th$3,388$2.0K$5.0K$10.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,041.74
Median
$3,311.31
Typical High
$3,311.31
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,949.84
Median
$2,290.87
Typical High
$2,754.23
Cigna
Setting
Facility
Modifier
Global
Typical Low
$5,623.41
Median
$5,623.41
Typical High
$5,623.41
Cigna
Setting
Professional
Modifier
Global
Typical Low
$4,073.80
Median
$5,623.41
Typical High
$6,918.31
Medica
Setting
Facility
Modifier
Global
Typical Low
$1,202.26
Median
$3,311.31
Typical High
$13,803.84
Medica
Setting
Professional
Modifier
Global
Typical Low
$1,479.11
Median
$1,479.11
Typical High
$14,454.40
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$4,168.69
Median
$6,760.83
Typical High
$7,943.28
United
Setting
Facility
Modifier
Global
Typical Low
$3,467.37
Median
$3,467.37
Typical High
$3,467.37
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$3,388.44
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$2,951.21
Median
$2,951.21
Typical High
$2,951.21