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Large Multi-Gene Tumor Sequencing Panel

South Carolina rates for HCPCS 81455

This laboratory service analyzes a large panel of genes from a tumor or blood sample to look for genetic changes that can help guide cancer diagnosis and treatment decisions. It examines many genes at once using next-generation sequencing technology, offering a broader look than smaller, more targeted gene panels. Results can help identify mutations that inform prognosis or point toward targeted therapies.

Rates data updated July 2026.

Facilitymedian $4,074 · 10th–90th $2,042$13,1830%20%10th90th$4,074Professionalmedian $2,291 · 10th–90th $1,318$3,0900%50%10th90th$2,291$10.0$50.0$200.0$1.0K$5.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,041.74
Median
$7,244.36
Typical High
$13,803.84
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,290.87
Median
$2,290.87
Typical High
$2,511.89
BCBS
Setting
Facility
Modifier
Global
Typical Low
$3,019.95
Median
$3,388.44
Typical High
$3,890.45
BCBS
Setting
Professional
Modifier
Global
Typical Low
$549.54
Median
$776.25
Typical High
$3,981.07
Cigna
Setting
Facility
Modifier
Global
Typical Low
$5,495.41
Median
$9,549.93
Typical High
$16,595.87
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,318.26
Median
$1,698.24
Typical High
$3,548.13
Medcost
Setting
Facility
Modifier
Global
Typical Low
$2,187.76
Median
$2,630.27
Typical High
$3,890.45
United
Setting
Facility
Modifier
Global
Typical Low
$1,621.81
Median
$2,951.21
Typical High
$3,467.37
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$2,951.21