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Large Multi-Gene Tumor Sequencing Panel

New York rates for HCPCS 81455

This laboratory service analyzes a large panel of genes from a tumor or blood sample to look for genetic changes that can help guide cancer diagnosis and treatment decisions. It examines many genes at once using next-generation sequencing technology, offering a broader look than smaller, more targeted gene panels. Results can help identify mutations that inform prognosis or point toward targeted therapies.

Rates data updated July 2026.

How much does Large Multi-Gene Tumor Sequencing Panel cost?

$2,951

Typical negotiated rate. In New York, July 2026.

Insurers have agreed to pay about $2,951 for this service. The price depends on where it is billed: about $2,344 from a physician practice, and about $5,012 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 10 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$2,344$1,175 to $3,090
FacilityA hospital or hospital-owned outpatient department$5,012$3,090 to $7,244

How much rates vary

Facilitymedian $5,012 · 10th to 90th $2,455 to $7,943Professionalmedian $2,344 · 10th to 90th $1,175 to $4,898
$100.0$1.0K$10.0K$100.0Kfacility $5,012professional $2,344

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,754.23
Median
$5,128.61
Typical High
$7,943.28
Aetna
Setting
Professional
Modifier
Global
Typical Low
$724.44
Median
$2,454.71
Typical High
$6,760.83
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$2,951.21
Median
$2,951.21
Typical High
$7,585.78
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,174.90
Median
$1,174.90
Typical High
$4,265.80
CDPHP
Setting
Facility
Modifier
Global
Typical Low
$1,737.80
Median
$2,951.21
Typical High
$2,951.21
CDPHP
Setting
Professional
Modifier
Global
Typical Low
$2,951.21
Median
$2,951.21
Typical High
$2,951.21
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,818.38
Median
$6,309.57
Typical High
$7,585.78
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,778.28
Median
$3,981.07
Typical High
$14,125.38
Emblem Health
Setting
Facility
Modifier
Global
Typical Low
$2,951.21
Median
$4,786.30
Typical High
$11,220.18
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$1,445.44
Median
$2,041.74
Typical High
$5,248.07
Excellus BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,949.84
Median
$2,754.23
Typical High
$5,248.07
Highmark BCBS
Setting
Facility
Modifier
Global
Typical Low
$2,290.87
Median
$2,290.87
Typical High
$6,165.95
MVP Health Care
Setting
Facility
Modifier
Global
Typical Low
$13.80
Median
$3,801.89
Typical High
$50,118.72
MVP Health Care
Setting
Professional
Modifier
Global
Typical Low
$645.65
Median
$2,951.21
Typical High
$5,128.61
United
Setting
Facility
Modifier
Global
Typical Low
$1,905.46
Median
$2,951.21
Typical High
$3,630.78
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$2,041.74
Typical High
$4,677.35
Univera
Setting
Facility
Modifier
Global
Typical Low
$2,454.71
Median
$2,454.71
Typical High
$3,090.30
Univera
Setting
Professional
Modifier
Global
Typical Low
$1,862.09
Median
$2,754.23
Typical High
$6,918.31

Where New York sits

The same service costs 6.2 times more in North Dakota than in Vermont. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

New York $2,951 · 14th of 51
ND $4,467VT $724

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.