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Large Multi-Gene Tumor Sequencing Panel

Minnesota rates for HCPCS 81455

This laboratory service analyzes a large panel of genes from a tumor or blood sample to look for genetic changes that can help guide cancer diagnosis and treatment decisions. It examines many genes at once using next-generation sequencing technology, offering a broader look than smaller, more targeted gene panels. Results can help identify mutations that inform prognosis or point toward targeted therapies.

Rates data updated July 2026.

Facilitymedian $6,457 · 10th–90th $1,820$21,3800%10%20%10th90th$6,457Professionalmedian $2,239 · 10th–90th $1,820$4,2660%20%40%10th90th$2,239$10.0$50.0$200.0$1.0K$5.0K$20.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,754.23
Median
$2,754.23
Typical High
$2,754.23
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,949.84
Median
$2,754.23
Typical High
$8,709.64
BCBS
Setting
Facility
Modifier
Global
Typical Low
$229.09
Median
$2,238.72
Typical High
$2,238.72
BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,819.70
Median
$2,238.72
Typical High
$2,238.72
Cigna
Setting
Facility
Modifier
Global
Typical Low
$5,623.41
Median
$10,000.00
Typical High
$27,542.29
Cigna
Setting
Professional
Modifier
Global
Typical Low
$3,388.44
Median
$4,265.80
Typical High
$6,025.60
Health Partners
Setting
Facility
Modifier
Global
Typical Low
$6,456.54
Median
$9,332.54
Typical High
$21,379.62
Health Partners
Setting
Professional
Modifier
Global
Typical Low
$3,388.44
Median
$3,388.44
Typical High
$5,623.41
Medica
Setting
Facility
Modifier
Global
Typical Low
$1,819.70
Median
$4,677.35
Typical High
$9,120.11
Medica
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$6,760.83
United
Setting
Facility
Modifier
Global
Typical Low
$2,884.03
Median
$3,388.44
Typical High
$3,981.07
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$2,951.21
Typical High
$6,309.57