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Large Multi-Gene Tumor Sequencing Panel

Maryland rates for HCPCS 81455

This laboratory service analyzes a large panel of genes from a tumor or blood sample to look for genetic changes that can help guide cancer diagnosis and treatment decisions. It examines many genes at once using next-generation sequencing technology, offering a broader look than smaller, more targeted gene panels. Results can help identify mutations that inform prognosis or point toward targeted therapies.

Rates data updated July 2026.

Facilitymedian $2,138 · 10th–90th $1,479$3,9810%10%20%10th90th$2,138Professionalmedian $2,344 · 10th–90th $1,288$6,0260%10%20%10th90th$2,344$50.0$200.0$1.0K$5.0K$20.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$1,621.81
Median
$2,137.96
Typical High
$3,981.07
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,905.46
Median
$2,398.83
Typical High
$19,054.61
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$2,089.30
Median
$2,089.30
Typical High
$2,630.27
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,445.44
Median
$1,905.46
Typical High
$3,801.89
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,548.82
Median
$2,089.30
Typical High
$5,128.61
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$2,951.21
Median
$3,467.37
Typical High
$4,365.16
United
Setting
Facility
Modifier
Global
Typical Low
$1,230.27
Median
$1,380.38
Typical High
$2,951.21
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,318.26
Typical High
$2,691.53
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$1,174.90
Median
$1,995.26
Typical High
$2,951.21