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Large Multi-Gene Tumor Sequencing Panel

Kentucky rates for HCPCS 81455

This laboratory service analyzes a large panel of genes from a tumor or blood sample to look for genetic changes that can help guide cancer diagnosis and treatment decisions. It examines many genes at once using next-generation sequencing technology, offering a broader look than smaller, more targeted gene panels. Results can help identify mutations that inform prognosis or point toward targeted therapies.

Rates data updated July 2026.

Facilitymedian $3,090 · 10th–90th $2,399$7,0790%20%10th90th$3,090Professionalmedian $1,318 · 10th–90th $794$3,1620%20%10th90th$1,318$100.0$200.0$500.0$1.0K$2.0K$5.0K$10.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,398.83
Median
$2,951.21
Typical High
$7,079.46
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,041.74
Median
$2,344.23
Typical High
$3,090.30
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$1,862.09
Median
$2,951.21
Typical High
$3,090.30
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$100.00
Median
$1,174.90
Typical High
$1,174.90
CareSource
Setting
Facility
Modifier
Global
Typical Low
$2,951.21
Median
$3,981.07
Typical High
$4,073.80
CareSource
Setting
Professional
Modifier
Global
Typical Low
$2,951.21
Median
$3,801.89
Typical High
$4,786.30
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,290.87
Median
$4,265.80
Typical High
$6,165.95
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,348.96
Median
$14,125.38
Typical High
$14,125.38
United
Setting
Facility
Modifier
Global
Typical Low
$1,318.26
Median
$2,951.21
Typical High
$2,951.21
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$2,951.21