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Large Multi-Gene Tumor Sequencing Panel

Indiana rates for HCPCS 81455

This laboratory service analyzes a large panel of genes from a tumor or blood sample to look for genetic changes that can help guide cancer diagnosis and treatment decisions. It examines many genes at once using next-generation sequencing technology, offering a broader look than smaller, more targeted gene panels. Results can help identify mutations that inform prognosis or point toward targeted therapies.

Rates data updated July 2026.

Facilitymedian $2,951 · 10th–90th $2,884$8,7100%20%40%10th90th$2,951Professionalmedian $2,399 · 10th–90th $1,175$2,6920%50%10th90th$2,399$10.0$50.0$200.0$1.0K$5.0K$20.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,884.03
Median
$3,467.37
Typical High
$6,309.57
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,344.23
Median
$2,398.83
Typical High
$2,630.27
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$2,951.21
Median
$2,951.21
Typical High
$8,709.64
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,174.90
Median
$1,174.90
Typical High
$2,238.72
CareSource
Setting
Facility
Modifier
Global
Typical Low
$2,344.23
Median
$2,951.21
Typical High
$4,073.80
CareSource
Setting
Professional
Modifier
Global
Typical Low
$2,951.21
Median
$3,235.94
Typical High
$4,073.80
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,905.46
Median
$2,951.21
Typical High
$6,760.83
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,348.96
Median
$2,630.27
Typical High
$4,168.69
United
Setting
Facility
Modifier
Global
Typical Low
$1,621.81
Median
$2,951.21
Typical High
$2,951.21
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,737.80
Typical High
$3,235.94