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Large Multi-Gene Tumor Sequencing Panel

Iowa rates for HCPCS 81455

This laboratory service analyzes a large panel of genes from a tumor or blood sample to look for genetic changes that can help guide cancer diagnosis and treatment decisions. It examines many genes at once using next-generation sequencing technology, offering a broader look than smaller, more targeted gene panels. Results can help identify mutations that inform prognosis or point toward targeted therapies.

Rates data updated July 2026.

Facilitymedian $4,467 · 10th–90th $2,239$8,5110%10%20%10th90th$4,467Professionalmedian $2,630 · 10th–90th $1,738$19,0550%10%20%10th90th$2,630$10.0$50.0$200.0$1.0K$5.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,238.72
Median
$5,495.41
Typical High
$8,511.38
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,905.46
Median
$2,511.89
Typical High
$19,054.61
Cigna
Setting
Facility
Modifier
Global
Typical Low
$4,265.80
Median
$4,265.80
Typical High
$4,265.80
Cigna
Setting
Professional
Modifier
Global
Typical Low
$3,467.37
Median
$5,623.41
Typical High
$6,918.31
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$2,454.71
Median
$4,786.30
Typical High
$6,165.95
Medica
Setting
Facility
Modifier
Global
Typical Low
$2,754.23
Median
$3,467.37
Typical High
$7,762.47
Medica
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$2,951.21
Typical High
$11,481.54
Midlands
Setting
Professional
Modifier
Global
Typical Low
$3,630.78
Median
$3,890.45
Typical High
$3,890.45
Oscar Health
Setting
Professional
Modifier
Global
Typical Low
$2,951.21
Median
$3,162.28
Typical High
$6,165.95
United
Setting
Facility
Modifier
Global
Typical Low
$2,951.21
Median
$2,951.21
Typical High
$6,456.54
United
Setting
Professional
Modifier
Global
Typical Low
$1,737.80
Median
$1,737.80
Typical High
$6,760.83
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$2,290.87
Median
$2,951.21
Typical High
$2,951.21