Large Multi-Gene Tumor Sequencing Panel

Delaware rates for HCPCS 81455

This laboratory service analyzes a large panel of genes from a tumor or blood sample to look for genetic changes that can help guide cancer diagnosis and treatment decisions. It examines many genes at once using next-generation sequencing technology, offering a broader look than smaller, more targeted gene panels. Results can help identify mutations that inform prognosis or point toward targeted therapies.

Rates data updated October 2026.

How much does Large Multi-Gene Tumor Sequencing Panel cost?

$1,950

Typical negotiated rate. In Delaware, October 2026.

Insurers have agreed to pay about $1,950 for this service. The price depends on where it is billed: about $1,950 from a physician practice, and about $2,399 from a hospital or other facility.

Few insurers publish rates for this combination, so treat this figure as a rough guide.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed by	Who charges it	Typical	Range
Physician practiceA doctor's office, clinic or independent provider	A doctor's office, clinic or independent provider	$1,950	$1,318 to $2,399
FacilityA hospital or hospital-owned outpatient department	A hospital or hospital-owned outpatient department	$2,399	$1,905 to $4,266

How much rates vary

Facilitymedian $2,399 · 10th to 90th $151 to $9,772Professionalmedian $1,950 · 10th to 90th $1,230 to $4,169

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier	Facility/Professional	Modifier	Typical Low	Median	Typical High
Aetna Setting Facility Modifier None Typical Low $2,398.83 Median $2,398.83 Typical High $2,398.83	Facility	None	$2,398.83	$2,398.83	$2,398.83
Aetna Setting Professional Modifier None Typical Low $1,862.09 Median $2,398.83 Typical High $2,454.71	Professional	None	$1,862.09	$2,398.83	$2,454.71
Cigna Setting Facility Modifier None Typical Low $1,905.46 Median $1,905.46 Typical High $4,265.80	Facility	None	$1,905.46	$1,905.46	$4,265.80
Cigna Setting Professional Modifier None Typical Low $1,949.84 Median $3,388.44 Typical High $14,125.38	Professional	None	$1,949.84	$3,388.44	$14,125.38
Highmark BCBS Setting Facility Modifier None Typical Low $151.36 Median $151.36 Typical High $9,772.37	Facility	None	$151.36	$151.36	$9,772.37
United Setting Professional Modifier None Typical Low $1,230.27 Median $1,737.80 Typical High $4,365.16	Professional	None	$1,230.27	$1,737.80	$4,365.16

Where Delaware sits

The same service costs 5.4 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Delaware· 43rd of 51

$1,950

AK $6,607AL $1,230

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.