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Large Multi-Gene Tumor Sequencing Panel

Colorado rates for HCPCS 81455

This laboratory service analyzes a large panel of genes from a tumor or blood sample to look for genetic changes that can help guide cancer diagnosis and treatment decisions. It examines many genes at once using next-generation sequencing technology, offering a broader look than smaller, more targeted gene panels. Results can help identify mutations that inform prognosis or point toward targeted therapies.

Rates data updated July 2026.

Facilitymedian $7,079 · 10th–90th $2,239$14,7910%5%10%10th90th$7,079Professionalmedian $2,239 · 10th–90th $1,230$3,0900%20%40%10th90th$2,239$1.0K$2.0K$5.0K$10.0K$20.0K$50.0K$100.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$1,862.09
Median
$6,456.54
Typical High
$13,803.84
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,949.84
Median
$2,344.23
Typical High
$3,090.30
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$3,630.78
Median
$8,709.64
Typical High
$14,791.08
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$1,174.90
Median
$1,230.27
Typical High
$2,238.72
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,548.82
Median
$1,905.46
Typical High
$7,762.47
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,348.96
Median
$1,548.82
Typical High
$4,265.80
Denver HMP
Setting
Facility
Modifier
Global
Typical Low
$2,089.30
Median
$2,951.21
Typical High
$4,365.16
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$2,884.03
Median
$4,168.69
Typical High
$8,709.64
Select Health
Setting
Facility
Modifier
Global
Typical Low
$3,090.30
Median
$5,370.32
Typical High
$6,165.95
Select Health
Setting
Professional
Modifier
Global
Typical Low
$2,041.74
Median
$2,951.21
Typical High
$4,365.16
United
Setting
Facility
Modifier
Global
Typical Low
$1,778.28
Median
$2,951.21
Typical High
$4,365.16
United
Setting
Professional
Modifier
Global
Typical Low
$1,230.27
Median
$1,230.27
Typical High
$2,137.96