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JAK2 V617F Gene Change Test

Wyoming rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

How much does JAK2 V617F Gene Change Test cost?

$115

Typical negotiated rate. In Wyoming, July 2026.

Insurers have agreed to pay about $115 for this service. The price depends on where it is billed: about $115 from a physician practice, and about $309 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$115$61.66 to $141
FacilityA hospital or hospital-owned outpatient department$309$158 to $309

How much rates vary

Facilitymedian $309 · 10th to 90th $112 to $550Professionalmedian $115 · 10th to 90th $62 to $295
$50$100$200$500$1Kfacility $309professional $115

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$309.03
Typical High
$549.54
Aetna
Setting
Professional
Modifier
Global
Typical Low
$61.66
Median
$91.20
Typical High
$95.50
BCBS
Setting
Facility
Modifier
Global
Typical Low
$158.49
Median
$158.49
Typical High
$190.55
BCBS
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$141.25
Typical High
$295.12
Cigna
Setting
Facility
Modifier
Global
Typical Low
$181.97
Median
$181.97
Typical High
$181.97
Cigna
Setting
Professional
Modifier
Global
Typical Low
$63.10
Median
$63.10
Typical High
$218.78
United
Setting
Facility
Modifier
Global
Typical Low
$112.20
Median
$112.20
Typical High
$112.20
United
Setting
Professional
Modifier
Global
Typical Low
$38.90
Median
$52.48
Typical High
$125.89

Where Wyoming sits

The same service costs 3.1 times more in Nebraska than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Wyoming· 12th of 51

$115

NE $204VT $66.07

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.