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JAK2 V617F Gene Change Test

Wyoming rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

Facilitymedian $309 · 10th–90th $112$5500%20%10th90th$309Professionalmedian $115 · 10th–90th $62$2950%10%20%10th90th$115$50.0$100.0$200.0$500.0$1.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Small sample; interpret with caution. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$309.03
Typical High
$549.54
Aetna
Setting
Professional
Modifier
Global
Typical Low
$61.66
Median
$91.20
Typical High
$95.50
BCBS
Setting
Facility
Modifier
Global
Typical Low
$158.49
Median
$158.49
Typical High
$190.55
BCBS
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$141.25
Typical High
$295.12
Cigna
Setting
Facility
Modifier
Global
Typical Low
$181.97
Median
$181.97
Typical High
$181.97
Cigna
Setting
Professional
Modifier
Global
Typical Low
$63.10
Median
$63.10
Typical High
$218.78
United
Setting
Facility
Modifier
Global
Typical Low
$112.20
Median
$112.20
Typical High
$112.20
United
Setting
Professional
Modifier
Global
Typical Low
$38.90
Median
$52.48
Typical High
$125.89