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JAK2 V617F Gene Change Test

Vermont rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

Facilitymedian $537 · 10th–90th $91$6170%20%10th90th$537Professionalmedian $66 · 10th–90th $58$870%20%10th90th$66$50.0$100.0$200.0$500.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Small sample; interpret with caution. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$66.07
Typical High
$87.10
BCBS
Setting
Facility
Modifier
Global
Typical Low
$537.03
Median
$537.03
Typical High
$537.03
Cigna
Setting
Facility
Modifier
Global
Typical Low
$154.88
Median
$616.60
Typical High
$616.60
Cigna
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$131.83
Typical High
$229.09
MVP Health Care
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$91.20
Typical High
$91.20
MVP Health Care
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$91.20
Typical High
$125.89
United
Setting
Professional
Modifier
Global
Typical Low
$54.95
Median
$125.89
Typical High
$251.19