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JAK2 V617F Gene Change Test

Virginia rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

How much does JAK2 V617F Gene Change Test cost?

$91.20

Typical negotiated rate. In Virginia, July 2026.

Insurers have agreed to pay about $91.20 for this service. The price depends on where it is billed: about $72.44 from a physician practice, and about $138 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$72.44$54.95 to $95.50
FacilityA hospital or hospital-owned outpatient department$138$91.20 to $240

How much rates vary

Facilitymedian $138 · 10th to 90th $91 to $468Professionalmedian $72 · 10th to 90th $46 to $182
$50$200$1K$5Kfacility $138professional $72

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$87.10
Median
$223.87
Typical High
$524.81
Aetna
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$87.10
Typical High
$239.88
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$91.20
Typical High
$363.08
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$45.71
Median
$45.71
Typical High
$75.86
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$169.82
Typical High
$257.04
Cigna
Setting
Facility
Modifier
Global
Typical Low
$93.33
Median
$223.87
Typical High
$467.74
Cigna
Setting
Professional
Modifier
Global
Typical Low
$50.12
Median
$61.66
Typical High
$190.55
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$100.00
Typical High
$128.82
Medcost
Setting
Facility
Modifier
Global
Typical Low
$75.86
Median
$123.03
Typical High
$173.78
Medcost
Setting
Professional
Modifier
Global
Typical Low
$70.79
Median
$123.03
Typical High
$190.55
Sentara
Setting
Facility
Modifier
Global
Typical Low
$87.10
Median
$125.89
Typical High
$10,000.00
Sentara
Setting
Professional
Modifier
Global
Typical Low
$87.10
Median
$125.89
Typical High
$10,000.00
United
Setting
Facility
Modifier
Global
Typical Low
$61.66
Median
$91.20
Typical High
$151.36
United
Setting
Professional
Modifier
Global
Typical Low
$38.90
Median
$54.95
Typical High
$125.89

Where Virginia sits

The same service costs 3.1 times more in Nebraska than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 29th of 51

$91.20

NE $204VT $66.07

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.