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JAK2 V617F Gene Change Test

Virginia rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated October 2026.

How much does JAK2 V617F Gene Change Test cost?

$87.10

Typical negotiated rate. In Virginia, October 2026.

Insurers have agreed to pay about $87.10 for this service. The price depends on where it is billed: about $69.18 from a physician practice, and about $138 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$69.18$54.95 to $91.20
FacilityA hospital or hospital-owned outpatient department$138$91.20 to $224

How much rates vary

Facilitymedian $138 · 10th to 90th $91 to $457Professionalmedian $69 · 10th to 90th $46 to $155
$50$200$1K$5Kfacility $138professional $69

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$69.18
Median
$128.82
Typical High
$239.88
Aetna
Setting
Professional
Modifier
None
Typical Low
$69.18
Median
$70.79
Typical High
$109.65
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$91.20
Median
$91.20
Typical High
$446.68
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$43.65
Median
$54.95
Typical High
$75.86
CareFirst
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$74.13
Typical High
$87.10
Cigna
Setting
Facility
Modifier
None
Typical Low
$93.33
Median
$177.83
Typical High
$323.59
Cigna
Setting
Professional
Modifier
None
Typical Low
$50.12
Median
$69.18
Typical High
$181.97
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$87.10
Median
$100.00
Typical High
$128.82
Medcost
Setting
Facility
Modifier
None
Typical Low
$169.82
Median
$169.82
Typical High
$181.97
Medcost
Setting
Professional
Modifier
None
Typical Low
$70.79
Median
$123.03
Typical High
$125.89
Sentara
Setting
Facility
Modifier
None
Typical Low
$87.10
Median
$154.88
Typical High
$10,232.93
Sentara
Setting
Professional
Modifier
None
Typical Low
$87.10
Median
$131.83
Typical High
$4,570.88
United
Setting
Facility
Modifier
None
Typical Low
$109.65
Median
$109.65
Typical High
$109.65
United
Setting
Professional
Modifier
None
Typical Low
$38.90
Median
$54.95
Typical High
$144.54
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$34.67
Median
$34.67
Typical High
$43.65
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$13.80
Median
$13.80
Typical High
$17.38

Where Virginia sits

The same service costs 3.2 times more in Alaska than in Connecticut. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 30th of 51

$87.10

AK $204CT $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.