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JAK2 V617F Gene Change Test

Utah rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

Facilitymedian $105 · 10th–90th $58$1820%20%10th90th$105Professionalmedian $72 · 10th–90th $52$1260%20%10th90th$72$50.0$100.0$200.0$500.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$57.54
Median
$123.03
Typical High
$181.97
Aetna
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$57.54
Typical High
$57.54
Cigna
Setting
Facility
Modifier
Global
Typical Low
$77.62
Median
$95.50
Typical High
$251.19
Cigna
Setting
Professional
Modifier
Global
Typical Low
$42.66
Median
$109.65
Typical High
$194.98
Regence BlueShield
Setting
Facility
Modifier
Global
Typical Low
$104.71
Median
$104.71
Typical High
$416.87
Regence BlueShield
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$77.62
Typical High
$141.25
Select Health
Setting
Facility
Modifier
Global
Typical Low
$64.57
Median
$64.57
Typical High
$64.57
U of Utah Health Plan
Setting
Professional
Modifier
Global
Typical Low
$72.44
Median
$81.28
Typical High
$138.04
United
Setting
Professional
Modifier
Global
Typical Low
$38.90
Median
$52.48
Typical High
$125.89