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JAK2 V617F Gene Change Test

South Dakota rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

How much does JAK2 V617F Gene Change Test cost?

$174

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $174 for this service. The price depends on where it is billed: about $174 from a physician practice, and about $263 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$174$70.79 to $251
FacilityA hospital or hospital-owned outpatient department$263$174 to $427

How much rates vary

Facilitymedian $263 · 10th to 90th $105 to $427Professionalmedian $174 · 10th to 90th $62 to $447
$100$200$500facility $263professional $174

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$263.03
Median
$309.03
Typical High
$426.58
Aetna
Setting
Professional
Modifier
Global
Typical Low
$61.66
Median
$95.50
Typical High
$446.68
Avera
Setting
Facility
Modifier
Global
Typical Low
$85.11
Median
$93.33
Typical High
$138.04
Avera
Setting
Professional
Modifier
Global
Typical Low
$95.50
Median
$95.50
Typical High
$95.50
Cigna
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$173.78
Cigna
Setting
Professional
Modifier
Global
Typical Low
$131.83
Median
$173.78
Typical High
$218.78
Medica
Setting
Facility
Modifier
Global
Typical Low
$87.10
Median
$104.71
Typical High
$346.74
Medica
Setting
Professional
Modifier
Global
Typical Low
$54.95
Median
$64.57
Typical High
$457.09
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$138.04
Median
$218.78
Typical High
$251.19
United
Setting
Professional
Modifier
Global
Typical Low
$38.90
Median
$64.57
Typical High
$125.89
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$91.20
Typical High
$91.20

Where South Dakota sits

The same service costs 3.1 times more in Nebraska than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 3rd of 51

$174

NE $204VT $66.07

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.