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JAK2 V617F Gene Change Test

South Dakota rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated October 2026.

How much does JAK2 V617F Gene Change Test cost?

$105

Typical negotiated rate. In South Dakota, October 2026.

Insurers have agreed to pay about $105 for this service. The price depends on where it is billed: about $105 from a physician practice, and about $105 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$105$83.18 to $186
FacilityA hospital or hospital-owned outpatient department$105$105 to $174

How much rates vary

Facilitymedian $105 · 10th to 90th $87 to $174Professionalmedian $105 · 10th to 90th $62 to $219
$50$100$200$500facility $105professional $105

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$64.57
Median
$104.71
Typical High
$436.52
Aetna
Setting
Professional
Modifier
None
Typical Low
$61.66
Median
$61.66
Typical High
$87.10
Cigna
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$173.78
Cigna
Setting
Professional
Modifier
None
Typical Low
$104.71
Median
$173.78
Typical High
$218.78
Medica
Setting
Facility
Modifier
None
Typical Low
$87.10
Median
$104.71
Typical High
$147.91
Medica
Setting
Professional
Modifier
None
Typical Low
$54.95
Median
$83.18
Typical High
$190.55
Sanford Health Plan
Setting
Professional
Modifier
None
Typical Low
$151.36
Median
$213.80
Typical High
$251.19
United
Setting
Professional
Modifier
None
Typical Low
$38.90
Median
$64.57
Typical High
$125.89
Wellmark
Setting
Professional
Modifier
None
Typical Low
$91.20
Median
$91.20
Typical High
$91.20

Where South Dakota sits

The same service costs 3.2 times more in Alaska than in Connecticut. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 19th of 51

$105

AK $204CT $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.