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JAK2 V617F Gene Change Test

Rhode Island rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

Facilitymedian $204 · 10th–90th $110$3890%10%20%10th90th$204Professionalmedian $83 · 10th–90th $58$1050%20%10th90th$83$50.0$100.0$200.0$500.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$151.36
Median
$275.42
Typical High
$524.81
Aetna
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$87.10
Typical High
$87.10
BCBS
Setting
Facility
Modifier
Global
Typical Low
$104.71
Median
$112.20
Typical High
$186.21
BCBS
Setting
Professional
Modifier
Global
Typical Low
$69.18
Median
$69.18
Typical High
$104.71
Cigna
Setting
Facility
Modifier
Global
Typical Low
$218.78
Median
$281.84
Typical High
$389.05
Cigna
Setting
Professional
Modifier
Global
Typical Low
$70.79
Median
$70.79
Typical High
$138.04
United
Setting
Facility
Modifier
Global
Typical Low
$109.65
Median
$109.65
Typical High
$173.78
United
Setting
Professional
Modifier
Global
Typical Low
$38.90
Median
$75.86
Typical High
$181.97