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JAK2 V617F Gene Change Test

Ohio rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated October 2026.

How much does JAK2 V617F Gene Change Test cost?

$75.86

Typical negotiated rate. In Ohio, October 2026.

Insurers have agreed to pay about $75.86 for this service. The price depends on where it is billed: about $54.95 from a physician practice, and about $135 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$54.95$45.71 to $93.33
FacilityA hospital or hospital-owned outpatient department$135$97.72 to $204

How much rates vary

Facilitymedian $135 · 10th to 90th $83 to $363Professionalmedian $55 · 10th to 90th $46 to $204
$50$100$200$500facility $135professional $55

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$91.20
Median
$204.17
Typical High
$407.38
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$43.65
Median
$100.00
Typical High
$269.15
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$17.38
Median
$40.74
Typical High
$107.15
Aetna
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$87.10
Typical High
$478.63
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$36.31
Median
$36.31
Typical High
$281.84
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$14.79
Median
$14.79
Typical High
$112.20
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$74.13
Median
$107.15
Typical High
$169.82
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$45.71
Median
$45.71
Typical High
$120.23
CareSource
Setting
Professional
Modifier
None
Typical Low
$91.20
Median
$91.20
Typical High
$123.03
Cigna
Setting
Facility
Modifier
None
Typical Low
$89.13
Median
$120.23
Typical High
$630.96
Cigna
Setting
Professional
Modifier
None
Typical Low
$46.77
Median
$46.77
Typical High
$177.83
Medical Mutual of Ohio
Setting
Facility
Modifier
None
Typical Low
$97.72
Median
$131.83
Typical High
$630.96
Medical Mutual of Ohio
Setting
Professional
Modifier
None
Typical Low
$46.77
Median
$46.77
Typical High
$165.96
Molina
Setting
Professional
Modifier
None
Typical Low
$63.10
Median
$83.18
Typical High
$112.20
SummaCare
Setting
Professional
Modifier
None
Typical Low
$77.62
Median
$112.20
Typical High
$151.36
United
Setting
Facility
Modifier
None
Typical Low
$33.11
Median
$83.18
Typical High
$138.04
United
Setting
Professional
Modifier
None
Typical Low
$38.90
Median
$54.95
Typical High
$131.83

Where Ohio sits

The same service costs 3.2 times more in Alaska than in Connecticut. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Ohio· 41st of 51

$75.86

AK $204CT $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.