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JAK2 V617F Gene Change Test

New Jersey rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated October 2026.

How much does JAK2 V617F Gene Change Test cost?

$64.57

Typical negotiated rate. In New Jersey, October 2026.

Insurers have agreed to pay about $64.57 for this service. The price depends on where it is billed: about $64.57 from a physician practice, and about $398 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$64.57$57.54 to $67.61
FacilityA hospital or hospital-owned outpatient department$398$132 to $10,000

How much rates vary

Facilitymedian $398 · 10th to 90th $81 to $19,953Professionalmedian $65 · 10th to 90th $52 to $100
$100$1K$10Kfacility $398professional $65

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$57.54
Median
$81.28
Typical High
$151.36
Aetna
Setting
Professional
Modifier
None
Typical Low
$57.54
Median
$57.54
Typical High
$81.28
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$28.84
Median
$28.84
Typical High
$40.74
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$11.48
Median
$11.48
Typical High
$16.60
AmeriHealth
Setting
Facility
Modifier
None
Typical Low
$131.83
Median
$467.74
Typical High
$5,888.44
Cigna
Setting
Facility
Modifier
None
Typical Low
$104.71
Median
$257.04
Typical High
$446.68
Cigna
Setting
Professional
Modifier
None
Typical Low
$57.54
Median
$107.15
Typical High
$257.04
Emblem Health
Setting
Professional
Modifier
None
Typical Low
$64.57
Median
$120.23
Typical High
$131.83
Horizon BCBS
Setting
Facility
Modifier
None
Typical Low
$4,365.16
Median
$14,791.08
Typical High
$26,915.35
Horizon BCBS
Setting
Professional
Modifier
None
Typical Low
$64.57
Median
$64.57
Typical High
$64.57
United
Setting
Facility
Modifier
None
Typical Low
$83.18
Median
$83.18
Typical High
$83.18
United
Setting
Professional
Modifier
None
Typical Low
$38.90
Median
$54.95
Typical High
$93.33

Where New Jersey sits

The same service costs 3.2 times more in Alaska than in Connecticut. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

New Jersey· 49th of 51

$64.57

AK $204CT $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.