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JAK2 V617F Gene Change Test

New Hampshire rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

Facilitymedian $219 · 10th–90th $58$5250%10%10th90th$219Professionalmedian $91 · 10th–90th $58$1740%20%10th90th$91$10.0$20.0$50.0$100.0$200.0$500.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$57.54
Median
$218.78
Typical High
$588.84
Aetna
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$83.18
Typical High
$616.60
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$158.49
Median
$177.83
Typical High
$512.86
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$60.26
Median
$60.26
Typical High
$87.10
Cigna
Setting
Facility
Modifier
Global
Typical Low
$147.91
Median
$338.84
Typical High
$478.63
Cigna
Setting
Professional
Modifier
Global
Typical Low
$47.86
Median
$95.50
Typical High
$380.19
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$91.20
Typical High
$173.78
United
Setting
Facility
Modifier
Global
Typical Low
$588.84
Median
$588.84
Typical High
$588.84
United
Setting
Professional
Modifier
Global
Typical Low
$54.95
Median
$91.20
Typical High
$269.15