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JAK2 V617F Gene Change Test

Nebraska rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated October 2026.

How much does JAK2 V617F Gene Change Test cost?

$87.10

Typical negotiated rate. In Nebraska, October 2026.

Insurers have agreed to pay about $87.10 for this service. The price depends on where it is billed: about $60.26 from a physician practice, and about $224 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$60.26$54.95 to $182
FacilityA hospital or hospital-owned outpatient department$224$135 to $324

How much rates vary

Facilitymedian $224 · 10th to 90th $60 to $437Professionalmedian $60 · 10th to 90th $52 to $457
$50$100$200$500facility $224professional $60

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$60.26
Median
$204.17
Typical High
$218.78
Aetna
Setting
Professional
Modifier
None
Typical Low
$60.26
Median
$60.26
Typical High
$218.78
BCBS
Setting
Facility
Modifier
None
Typical Low
$181.97
Median
$309.03
Typical High
$616.60
Cigna
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$181.97
Typical High
$218.78
Medica
Setting
Facility
Modifier
None
Typical Low
$54.95
Median
$120.23
Typical High
$436.52
Medica
Setting
Professional
Modifier
None
Typical Low
$54.95
Median
$54.95
Typical High
$457.09
Midlands
Setting
Professional
Modifier
None
Typical Low
$165.96
Median
$165.96
Typical High
$165.96
Midlands
Setting
Professional
Modifier
None
Typical Low
$165.96
Median
$165.96
Typical High
$165.96
United
Setting
Facility
Modifier
None
Typical Low
$33.11
Median
$38.90
Typical High
$54.95
United
Setting
Professional
Modifier
None
Typical Low
$52.48
Median
$54.95
Typical High
$371.54

Where Nebraska sits

The same service costs 3.2 times more in Alaska than in Connecticut. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Nebraska· 34th of 51

$87.10

AK $204CT $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.