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JAK2 V617F Gene Change Test

Minnesota rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated October 2026.

How much does JAK2 V617F Gene Change Test cost?

$105

Typical negotiated rate. In Minnesota, October 2026.

Insurers have agreed to pay about $105 for this service. The price depends on where it is billed: about $91.20 from a physician practice, and about $288 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$91.20$79.43 to $117
FacilityA hospital or hospital-owned outpatient department$288$89.13 to $501

How much rates vary

Facilitymedian $288 · 10th to 90th $87 to $661Professionalmedian $91 · 10th to 90th $65 to $191
$50$100$200$500facility $288professional $91

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$75.86
Median
$416.87
Typical High
$724.44
Aetna
Setting
Professional
Modifier
None
Typical Low
$87.10
Median
$87.10
Typical High
$109.65
BCBS Minnesota
Setting
Facility
Modifier
None
Typical Low
$87.10
Median
$91.20
Typical High
$346.74
BCBS Minnesota
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$83.18
Typical High
$91.20
Cigna
Setting
Facility
Modifier
None
Typical Low
$181.97
Median
$295.12
Typical High
$851.14
Cigna
Setting
Professional
Modifier
None
Typical Low
$107.15
Median
$120.23
Typical High
$177.83
Health Partners
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$281.84
Typical High
$676.08
Health Partners
Setting
Professional
Modifier
None
Typical Low
$104.71
Median
$104.71
Typical High
$173.78
Medica
Setting
Facility
Modifier
None
Typical Low
$72.44
Median
$229.09
Typical High
$575.44
Medica
Setting
Professional
Modifier
None
Typical Low
$54.95
Median
$109.65
Typical High
$457.09
United
Setting
Facility
Modifier
None
Typical Low
$91.20
Median
$91.20
Typical High
$109.65
United
Setting
Professional
Modifier
None
Typical Low
$38.90
Median
$75.86
Typical High
$213.80
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$42.66
Median
$42.66
Typical High
$42.66
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$17.38
Median
$17.38
Typical High
$17.38
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$42.66
Median
$42.66
Typical High
$43.65
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$17.38
Median
$17.38
Typical High
$17.78

Where Minnesota sits

The same service costs 3.2 times more in Alaska than in Connecticut. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Minnesota· 16th of 51

$105

AK $204CT $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.