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JAK2 V617F Gene Change Test

Minnesota rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

How much does JAK2 V617F Gene Change Test cost?

$91.20

Typical negotiated rate. In Minnesota, July 2026.

Insurers have agreed to pay about $91.20 for this service. The price depends on where it is billed: about $91.20 from a physician practice, and about $251 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$91.20$89.13 to $105
FacilityA hospital or hospital-owned outpatient department$251$91.20 to $427

How much rates vary

Facilitymedian $251 · 10th to 90th $91 to $676Professionalmedian $91 · 10th to 90th $74 to $200
$50$100$200$500facility $251professional $91

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$87.10
Median
$269.15
Typical High
$457.09
Aetna
Setting
Professional
Modifier
Global
Typical Low
$61.66
Median
$95.50
Typical High
$446.68
BCBS
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$91.20
Typical High
$338.84
BCBS
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$91.20
Typical High
$91.20
Cigna
Setting
Facility
Modifier
Global
Typical Low
$186.21
Median
$309.03
Typical High
$851.14
Cigna
Setting
Professional
Modifier
Global
Typical Low
$107.15
Median
$134.90
Typical High
$186.21
Health Partners
Setting
Facility
Modifier
Global
Typical Low
$199.53
Median
$288.40
Typical High
$676.08
Health Partners
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$104.71
Typical High
$173.78
Medica
Setting
Facility
Modifier
Global
Typical Low
$77.62
Median
$223.87
Typical High
$489.78
Medica
Setting
Professional
Modifier
Global
Typical Low
$45.71
Median
$75.86
Typical High
$354.81
United
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$109.65
Typical High
$588.84
United
Setting
Professional
Modifier
Global
Typical Low
$54.95
Median
$100.00
Typical High
$467.74

Where Minnesota sits

The same service costs 3.1 times more in Nebraska than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Minnesota· 31st of 51

$91.20

NE $204VT $66.07

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.