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JAK2 V617F Gene Change Test

Minnesota rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

Facilitymedian $251 · 10th–90th $91$6760%10%10th90th$251Professionalmedian $91 · 10th–90th $74$2000%20%10th90th$91$10.0$20.0$50.0$100.0$200.0$500.0$1.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$87.10
Median
$269.15
Typical High
$457.09
Aetna
Setting
Professional
Modifier
Global
Typical Low
$61.66
Median
$95.50
Typical High
$446.68
BCBS
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$91.20
Typical High
$338.84
BCBS
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$91.20
Typical High
$91.20
Cigna
Setting
Facility
Modifier
Global
Typical Low
$186.21
Median
$309.03
Typical High
$851.14
Cigna
Setting
Professional
Modifier
Global
Typical Low
$107.15
Median
$134.90
Typical High
$186.21
Health Partners
Setting
Facility
Modifier
Global
Typical Low
$199.53
Median
$288.40
Typical High
$676.08
Health Partners
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$104.71
Typical High
$173.78
Medica
Setting
Facility
Modifier
Global
Typical Low
$77.62
Median
$223.87
Typical High
$489.78
Medica
Setting
Professional
Modifier
Global
Typical Low
$45.71
Median
$75.86
Typical High
$354.81
United
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$109.65
Typical High
$588.84
United
Setting
Professional
Modifier
Global
Typical Low
$54.95
Median
$100.00
Typical High
$467.74