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JAK2 V617F Gene Change Test

Maine rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

Facilitymedian $166 · 10th–90th $91$5250%10%20%10th90th$166Professionalmedian $91 · 10th–90th $55$1100%50%10th90th$91$50.0$100.0$200.0$500.0$1.0K$2.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$147.91
Typical High
$575.44
Aetna
Setting
Professional
Modifier
Global
Typical Low
$69.18
Median
$74.13
Typical High
$91.20
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$107.15
Median
$165.96
Typical High
$177.83
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$36.31
Median
$54.95
Typical High
$117.49
Cigna
Setting
Facility
Modifier
Global
Typical Low
$208.93
Median
$208.93
Typical High
$208.93
Cigna
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$91.20
Typical High
$93.33
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$91.20
Typical High
$109.65
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$147.91
Typical High
$977.24
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$69.18
Median
$91.20
Typical High
$102.33
United
Setting
Facility
Modifier
Global
Typical Low
$588.84
Median
$588.84
Typical High
$588.84
United
Setting
Professional
Modifier
Global
Typical Low
$54.95
Median
$91.20
Typical High
$186.21