go back

JAK2 V617F Gene Change Test

Maryland rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

How much does JAK2 V617F Gene Change Test cost?

$75.86

Typical negotiated rate. In Maryland, July 2026.

Insurers have agreed to pay about $75.86 for this service. Most negotiated rates run $66.07 to $178.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $191 · 10th to 90th $50 to $550Professionalmedian $76 · 10th to 90th $55 to $191
$50$100$200$500facility $191professional $76

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$50.12
Median
$190.55
Typical High
$549.54
Aetna
Setting
Professional
Modifier
Global
Typical Low
$61.66
Median
$77.62
Typical High
$190.55
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$66.07
Typical High
$83.18
Cigna
Setting
Professional
Modifier
Global
Typical Low
$50.12
Median
$67.61
Typical High
$162.18
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$109.65
Typical High
$138.04
United
Setting
Facility
Modifier
Global
Typical Low
$38.90
Median
$38.90
Typical High
$588.84
United
Setting
Professional
Modifier
Global
Typical Low
$41.69
Median
$52.48
Typical High
$91.20
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$45.71
Median
$89.13
Typical High
$89.13

Where Maryland sits

The same service costs 3.1 times more in Nebraska than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 48th of 51

$75.86

NE $204VT $66.07

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.