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JAK2 V617F Gene Change Test

Maryland rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

Facilitymedian $191 · 10th–90th $50$5500%10%10th90th$191Professionalmedian $76 · 10th–90th $55$1910%20%10th90th$76$2.0$10.0$50.0$200.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$50.12
Median
$190.55
Typical High
$549.54
Aetna
Setting
Professional
Modifier
Global
Typical Low
$61.66
Median
$77.62
Typical High
$190.55
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$66.07
Typical High
$83.18
Cigna
Setting
Professional
Modifier
Global
Typical Low
$50.12
Median
$67.61
Typical High
$162.18
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$109.65
Typical High
$138.04
United
Setting
Facility
Modifier
Global
Typical Low
$38.90
Median
$38.90
Typical High
$588.84
United
Setting
Professional
Modifier
Global
Typical Low
$41.69
Median
$52.48
Typical High
$91.20
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$45.71
Median
$89.13
Typical High
$89.13