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JAK2 V617F Gene Change Test

Kentucky rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated October 2026.

How much does JAK2 V617F Gene Change Test cost?

$75.86

Typical negotiated rate. In Kentucky, October 2026.

Insurers have agreed to pay about $75.86 for this service. The price depends on where it is billed: about $75.86 from a physician practice, and about $91.20 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$75.86$43.65 to $110
FacilityA hospital or hospital-owned outpatient department$91.20$74.13 to $126

How much rates vary

Facilitymedian $91 · 10th to 90th $58 to $200Professionalmedian $76 · 10th to 90th $44 to $263
$50$100$200$500facility $91professional $76

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$57.54
Median
$77.62
Typical High
$138.04
Aetna
Setting
Professional
Modifier
None
Typical Low
$64.57
Median
$74.13
Typical High
$91.20
Ambetter
Setting
Professional
Modifier
None
Typical Low
$63.10
Median
$63.10
Typical High
$63.10
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$57.54
Median
$91.20
Typical High
$95.50
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$33.11
Median
$43.65
Typical High
$107.15
CareSource
Setting
Facility
Modifier
None
Typical Low
$91.20
Median
$123.03
Typical High
$128.82
CareSource
Setting
Professional
Modifier
None
Typical Low
$91.20
Median
$120.23
Typical High
$151.36
Cigna
Setting
Facility
Modifier
None
Typical Low
$70.79
Median
$199.53
Typical High
$218.78
Cigna
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$446.68
Typical High
$446.68
United
Setting
Professional
Modifier
None
Typical Low
$50.12
Median
$75.86
Typical High
$154.88
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$32.36
Median
$37.15
Typical High
$45.71
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$12.88
Median
$14.79
Typical High
$18.20

Where Kentucky sits

The same service costs 3.2 times more in Alaska than in Connecticut. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Kentucky· 38th of 51

$75.86

AK $204CT $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.