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JAK2 V617F Gene Change Test

Kentucky rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

Facilitymedian $138 · 10th–90th $76$3390%10%20%10th90th$138Professionalmedian $72 · 10th–90th $44$1380%20%10th90th$72$50.0$100.0$200.0$500.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$75.86
Median
$138.04
Typical High
$338.84
Aetna
Setting
Professional
Modifier
Global
Typical Low
$64.57
Median
$75.86
Typical High
$602.56
Ambetter
Setting
Professional
Modifier
Global
Typical Low
$63.10
Median
$63.10
Typical High
$63.10
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$57.54
Median
$91.20
Typical High
$95.50
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$43.65
Median
$43.65
Typical High
$45.71
CareSource
Setting
Facility
Modifier
Global
Typical Low
$109.65
Median
$128.82
Typical High
$173.78
CareSource
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$120.23
Typical High
$147.91
Cigna
Setting
Facility
Modifier
Global
Typical Low
$70.79
Median
$199.53
Typical High
$218.78
Cigna
Setting
Professional
Modifier
Global
Typical Low
$45.71
Median
$446.68
Typical High
$446.68
United
Setting
Facility
Modifier
Global
Typical Low
$69.18
Median
$91.20
Typical High
$588.84
United
Setting
Professional
Modifier
Global
Typical Low
$39.81
Median
$75.86
Typical High
$125.89