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JAK2 V617F Gene Change Test

Indiana rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

How much does JAK2 V617F Gene Change Test cost?

$87.10

Typical negotiated rate. In Indiana, July 2026.

Insurers have agreed to pay about $87.10 for this service. The price depends on where it is billed: about $75.86 from a physician practice, and about $97.72 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$75.86$66.07 to $83.18
FacilityA hospital or hospital-owned outpatient department$97.72$91.20 to $200

How much rates vary

Facilitymedian $98 · 10th to 90th $91 to $275Professionalmedian $76 · 10th to 90th $44 to $112
$50$100$200$500$1Kfacility $98professional $76

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$128.82
Typical High
$338.84
Aetna
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$75.86
Typical High
$125.89
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$91.20
Typical High
$275.42
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$43.65
Median
$43.65
Typical High
$85.11
CareSource
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$91.20
Typical High
$128.82
CareSource
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$104.71
Typical High
$128.82
Cigna
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$91.20
Typical High
$239.88
Cigna
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$85.11
Typical High
$162.18
United
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$91.20
Typical High
$104.71
United
Setting
Professional
Modifier
Global
Typical Low
$38.90
Median
$72.44
Typical High
$125.89

Where Indiana sits

The same service costs 3.1 times more in Nebraska than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 36th of 51

$87.10

NE $204VT $66.07

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.