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JAK2 V617F Gene Change Test

Illinois rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated October 2026.

How much does JAK2 V617F Gene Change Test cost?

$70.79

Typical negotiated rate. In Illinois, October 2026.

Insurers have agreed to pay about $70.79 for this service. The price depends on where it is billed: about $70.79 from a physician practice, and about $178 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$70.79$3.98 to $75.86
FacilityA hospital or hospital-owned outpatient department$178$115 to $309

How much rates vary

Facilitymedian $178 · 10th to 90th $102 to $562Professionalmedian $71 · 10th to 90th $3 to $123
$5$20$100$500facility $178professional $71

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$79.43
Median
$134.90
Typical High
$275.42
Aetna
Setting
Professional
Modifier
None
Typical Low
$61.66
Median
$75.86
Typical High
$89.13
Ambetter
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$123.03
Typical High
$123.03
BCBS Illinois
Setting
Facility
Modifier
None
Typical Low
$109.65
Median
$162.18
Typical High
$1,148.15
BCBS Illinois
Setting
Professional
Modifier
None
Typical Low
$3.47
Median
$63.10
Typical High
$70.79
Cigna
Setting
Facility
Modifier
None
Typical Low
$102.33
Median
$213.80
Typical High
$398.11
Cigna
Setting
Professional
Modifier
None
Typical Low
$45.71
Median
$125.89
Typical High
$162.18
Hally Health
Setting
Professional
Modifier
None
Typical Low
$100.00
Median
$141.25
Typical High
$524.81
Hally Health
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
None
Typical Low
$120.23
Median
$120.23
Typical High
$120.23
United
Setting
Facility
Modifier
None
Typical Low
$91.20
Median
$109.65
Typical High
$114.82
United
Setting
Professional
Modifier
None
Typical Low
$38.90
Median
$60.26
Typical High
$97.72
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$37.15
Median
$66.07
Typical High
$138.04
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$15.14
Median
$26.30
Typical High
$54.95
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$37.15
Median
$37.15
Typical High
$41.69
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$14.79
Median
$15.14
Typical High
$16.60

Where Illinois sits

The same service costs 3.2 times more in Alaska than in Connecticut. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 45th of 51

$70.79

AK $204CT $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.