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JAK2 V617F Gene Change Test

Illinois rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

Facilitymedian $158 · 10th–90th $79$5010%5%10%10th90th$158Professionalmedian $74 · 10th–90th $3$1820%20%10th90th$74$5.0$20.0$100.0$500.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$79.43
Median
$158.49
Typical High
$501.19
Aetna
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$75.86
Typical High
$186.21
BCBS
Setting
Facility
Modifier
Global
Typical Low
$117.49
Median
$371.54
Typical High
$1,148.15
BCBS
Setting
Professional
Modifier
Global
Typical Low
$3.47
Median
$63.10
Typical High
$70.79
Cigna
Setting
Facility
Modifier
Global
Typical Low
$125.89
Median
$213.80
Typical High
$416.87
Cigna
Setting
Professional
Modifier
Global
Typical Low
$44.67
Median
$125.89
Typical High
$165.96
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$100.00
Median
$199.53
Typical High
$549.54
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$120.23
Median
$120.23
Typical High
$120.23
United
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$91.20
Typical High
$181.97
United
Setting
Professional
Modifier
Global
Typical Low
$38.90
Median
$74.13
Typical High
$218.78