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JAK2 V617F Gene Change Test

Iowa rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated October 2026.

How much does JAK2 V617F Gene Change Test cost?

$110

Typical negotiated rate. In Iowa, October 2026.

Insurers have agreed to pay about $110 for this service. The price depends on where it is billed: about $95.50 from a physician practice, and about $170 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$95.50$70.79 to $195
FacilityA hospital or hospital-owned outpatient department$170$110 to $234

How much rates vary

Facilitymedian $170 · 10th to 90th $91 to $257Professionalmedian $95 · 10th to 90th $55 to $437
$50$100$200$500facility $170professional $95

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$70.79
Median
$190.55
Typical High
$257.04
Aetna
Setting
Professional
Modifier
None
Typical Low
$61.66
Median
$70.79
Typical High
$109.65
Cigna
Setting
Professional
Modifier
None
Typical Low
$112.20
Median
$173.78
Typical High
$257.04
Hally Health
Setting
Professional
Modifier
None
Typical Low
$91.20
Median
$120.23
Typical High
$436.52
Medica
Setting
Facility
Modifier
None
Typical Low
$91.20
Median
$181.97
Typical High
$257.04
Medica
Setting
Professional
Modifier
None
Typical Low
$54.95
Median
$109.65
Typical High
$457.09
Midlands
Setting
Professional
Modifier
None
Typical Low
$112.20
Median
$112.20
Typical High
$120.23
Oscar Health
Setting
Professional
Modifier
None
Typical Low
$91.20
Median
$100.00
Typical High
$194.98
United
Setting
Facility
Modifier
None
Typical Low
$91.20
Median
$91.20
Typical High
$234.42
United
Setting
Professional
Modifier
None
Typical Low
$54.95
Median
$54.95
Typical High
$223.87
Wellmark
Setting
Professional
Modifier
None
Typical Low
$91.20
Median
$91.20
Typical High
$91.20
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$35.48
Median
$35.48
Typical High
$54.95
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$14.45
Median
$14.45
Typical High
$21.88

Where Iowa sits

The same service costs 3.2 times more in Alaska than in Connecticut. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Iowa· 12th of 51

$110

AK $204CT $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.