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JAK2 V617F Gene Change Test

Iowa rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

How much does JAK2 V617F Gene Change Test cost?

$110

Typical negotiated rate. In Iowa, July 2026.

Insurers have agreed to pay about $110 for this service. The price depends on where it is billed: about $89.13 from a physician practice, and about $200 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$89.13$70.79 to $234
FacilityA hospital or hospital-owned outpatient department$200$135 to $263

How much rates vary

Facilitymedian $200 · 10th to 90th $91 to $437Professionalmedian $89 · 10th to 90th $60 to $501
$100$200$500facility $200professional $89

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$199.53
Typical High
$676.08
Aetna
Setting
Professional
Modifier
Global
Typical Low
$70.79
Median
$79.43
Typical High
$602.56
Cigna
Setting
Facility
Modifier
Global
Typical Low
$199.53
Median
$199.53
Typical High
$199.53
Cigna
Setting
Professional
Modifier
Global
Typical Low
$117.49
Median
$173.78
Typical High
$218.78
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$162.18
Typical High
$436.52
Medica
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$109.65
Typical High
$251.19
Medica
Setting
Professional
Modifier
Global
Typical Low
$54.95
Median
$112.20
Typical High
$457.09
Midlands
Setting
Professional
Modifier
Global
Typical Low
$112.20
Median
$120.23
Typical High
$120.23
Oscar Health
Setting
Facility
Modifier
Global
Typical Low
$407.38
Median
$407.38
Typical High
$407.38
Oscar Health
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$100.00
Typical High
$194.98
United
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$91.20
Typical High
$208.93
United
Setting
Professional
Modifier
Global
Typical Low
$54.95
Median
$83.18
Typical High
$371.54
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$91.20
Typical High
$91.20

Where Iowa sits

The same service costs 3.1 times more in Nebraska than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Iowa· 17th of 51

$110

NE $204VT $66.07

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.