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JAK2 V617F Gene Change Test

Hawaii rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

Facilitymedian $91 · 10th–90th $76$1950%10%20%10th90th$91Professionalmedian $132 · 10th–90th $66$2190%10%10th90th$132$50.0$100.0$200.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$75.86
Median
$91.20
Typical High
$194.98
Aetna
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$66.07
Typical High
$141.25
Cigna
Setting
Professional
Modifier
Global
Typical Low
$109.65
Median
$109.65
Typical High
$109.65
HMSA
Setting
Professional
Modifier
Global
Typical Low
$125.89
Median
$162.18
Typical High
$177.83
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$100.00
Median
$109.65
Typical High
$138.04
United
Setting
Professional
Modifier
Global
Typical Low
$54.95
Median
$109.65
Typical High
$138.04
University Health Alliance
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$123.03
Typical High
$223.87