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JAK2 V617F Gene Change Test

Georgia rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

Facilitymedian $123 · 10th–90th $74$3390%10%20%10th90th$123Professionalmedian $85 · 10th–90th $51$2040%20%10th90th$85$20.0$100.0$500.0$2.0K$10.0K$50.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$165.96
Typical High
$630.96
Aetna
Setting
Professional
Modifier
Global
Typical Low
$60.26
Median
$85.11
Typical High
$186.21
Ambetter
Setting
Professional
Modifier
Global
Typical Low
$56.23
Median
$56.23
Typical High
$131.83
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$70.79
Median
$123.03
Typical High
$181.97
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$28.84
Median
$114.82
Typical High
$213.80
CareSource
Setting
Facility
Modifier
Global
Typical Low
$128.82
Median
$128.82
Typical High
$128.82
CareSource
Setting
Professional
Modifier
Global
Typical Low
$109.65
Median
$120.23
Typical High
$123.03
Cigna
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$147.91
Typical High
$281.84
Cigna
Setting
Professional
Modifier
Global
Typical Low
$45.71
Median
$93.33
Typical High
$239.88
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$83.18
Median
$120.23
Typical High
$199.53
Oscar Health
Setting
Facility
Modifier
Global
Typical Low
$575.44
Median
$575.44
Typical High
$676.08
Oscar Health
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$112.20
Typical High
$194.98
United
Setting
Facility
Modifier
Global
Typical Low
$75.86
Median
$83.18
Typical High
$112.20
United
Setting
Professional
Modifier
Global
Typical Low
$38.90
Median
$54.95
Typical High
$128.82