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JAK2 V617F Gene Change Test

Florida rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

How much does JAK2 V617F Gene Change Test cost?

$87.10

Typical negotiated rate. In Florida, July 2026.

Insurers have agreed to pay about $87.10 for this service. The price depends on where it is billed: about $79.43 from a physician practice, and about $195 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$79.43$66.07 to $91.20
FacilityA hospital or hospital-owned outpatient department$195$117 to $282

How much rates vary

Facilitymedian $195 · 10th to 90th $83 to $501Professionalmedian $79 · 10th to 90th $56 to $295
$10$20$50$100$200$500$1Kfacility $195professional $79

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$208.93
Typical High
$537.03
Aetna
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$79.43
Typical High
$446.68
Ambetter
Setting
Professional
Modifier
Global
Typical Low
$56.23
Median
$56.23
Typical High
$91.20
AvMed
Setting
Facility
Modifier
Global
Typical Low
$81.28
Median
$91.20
Typical High
$107.15
AvMed
Setting
Professional
Modifier
Global
Typical Low
$14.13
Median
$91.20
Typical High
$91.20
Cigna
Setting
Facility
Modifier
Global
Typical Low
$67.61
Median
$100.00
Typical High
$371.54
Cigna
Setting
Professional
Modifier
Global
Typical Low
$45.71
Median
$77.62
Typical High
$186.21
Florida Blue
Setting
Facility
Modifier
Global
Typical Low
$169.82
Median
$169.82
Typical High
$169.82
Florida Blue
Setting
Professional
Modifier
Global
Typical Low
$54.95
Median
$54.95
Typical High
$74.13
Molina
Setting
Professional
Modifier
Global
Typical Low
$54.95
Median
$60.26
Typical High
$158.49
United
Setting
Facility
Modifier
Global
Typical Low
$52.48
Median
$83.18
Typical High
$114.82
United
Setting
Professional
Modifier
Global
Typical Low
$38.90
Median
$52.48
Typical High
$186.21
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$51.29
Median
$91.20
Typical High
$91.20

Where Florida sits

The same service costs 3.1 times more in Nebraska than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Florida· 40th of 51

$87.10

NE $204VT $66.07

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.