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JAK2 V617F Gene Change Test

Delaware rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

How much does JAK2 V617F Gene Change Test cost?

$75.86

Typical negotiated rate. In Delaware, July 2026.

Insurers have agreed to pay about $75.86 for this service. The price depends on where it is billed: about $61.66 from a physician practice, and about $372 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$61.66$57.54 to $75.86
FacilityA hospital or hospital-owned outpatient department$372$95.50 to $776

How much rates vary

Facilitymedian $372 · 10th to 90th $76 to $813Professionalmedian $62 · 10th to 90th $58 to $275
$50$100$200$500facility $372professional $62

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$75.86
Median
$371.54
Typical High
$812.83
Aetna
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$61.66
Typical High
$275.42
Cigna
Setting
Facility
Modifier
Global
Typical Low
$60.26
Median
$60.26
Typical High
$60.26
Cigna
Setting
Professional
Modifier
Global
Typical Low
$60.26
Median
$60.26
Typical High
$169.82
Highmark BCBS
Setting
Facility
Modifier
Global
Typical Low
$47.86
Median
$234.42
Typical High
$446.68
United
Setting
Professional
Modifier
Global
Typical Low
$41.69
Median
$75.86
Typical High
$138.04

Where Delaware sits

The same service costs 3.1 times more in Nebraska than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Delaware· 46th of 51

$75.86

NE $204VT $66.07

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.