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JAK2 V617F Gene Change Test

Washington, DC rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

Facilitymedian $209 · 10th–90th $69$5750%20%10th90th$209Professionalmedian $69 · 10th–90th $66$1700%50%10th90th$69$0.1$0.5$2.0$10.0$50.0$200.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$69.18
Median
$208.93
Typical High
$575.44
Aetna
Setting
Professional
Modifier
Global
Typical Low
$67.61
Median
$69.18
Typical High
$70.79
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$117.49
Typical High
$407.38
Cigna
Setting
Facility
Modifier
Global
Typical Low
$147.91
Median
$154.88
Typical High
$346.74
Cigna
Setting
Professional
Modifier
Global
Typical Low
$54.95
Median
$107.15
Typical High
$416.87
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$177.83
Typical High
$186.21
United
Setting
Facility
Modifier
Global
Typical Low
$52.48
Median
$109.65
Typical High
$588.84
United
Setting
Professional
Modifier
Global
Typical Low
$38.90
Median
$87.10
Typical High
$467.74