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JAK2 V617F Gene Change Test

Arizona rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated October 2026.

How much does JAK2 V617F Gene Change Test cost?

$75.86

Typical negotiated rate. In Arizona, October 2026.

Insurers have agreed to pay about $75.86 for this service. The price depends on where it is billed: about $61.66 from a physician practice, and about $200 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$61.66$52.48 to $97.72
FacilityA hospital or hospital-owned outpatient department$200$100 to $302

How much rates vary

Facilitymedian $200 · 10th to 90th $62 to $398Professionalmedian $62 · 10th to 90th $39 to $457
$50$100$200$500facility $200professional $62

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$70.79
Median
$141.25
Typical High
$478.63
Aetna
Setting
Professional
Modifier
None
Typical Low
$61.66
Median
$61.66
Typical High
$79.43
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$30.90
Median
$30.90
Typical High
$33.88
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$12.30
Median
$12.30
Typical High
$13.49
BCBS
Setting
Facility
Modifier
None
Typical Low
$61.66
Median
$263.03
Typical High
$398.11
BCBS
Setting
Professional
Modifier
None
Typical Low
$87.10
Median
$91.20
Typical High
$158.49
Cigna
Setting
Facility
Modifier
None
Typical Low
$60.26
Median
$177.83
Typical High
$257.04
Cigna
Setting
Professional
Modifier
None
Typical Low
$46.77
Median
$100.00
Typical High
$354.81
Medica
Setting
Facility
Modifier
None
Typical Low
$61.66
Median
$74.13
Typical High
$158.49
Medica
Setting
Professional
Modifier
None
Typical Low
$38.90
Median
$52.48
Typical High
$457.09
United
Setting
Professional
Modifier
None
Typical Low
$38.90
Median
$52.48
Typical High
$54.95

Where Arizona sits

The same service costs 3.2 times more in Alaska than in Connecticut. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Arizona· 38th of 51

$75.86

AK $204CT $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.