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JAK2 V617F Gene Change Test

Arizona rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

How much does JAK2 V617F Gene Change Test cost?

$74.13

Typical negotiated rate. In Arizona, July 2026.

Insurers have agreed to pay about $74.13 for this service. The price depends on where it is billed: about $67.61 from a physician practice, and about $209 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$67.61$61.66 to $77.62
FacilityA hospital or hospital-owned outpatient department$209$132 to $347

How much rates vary

Facilitymedian $209 · 10th to 90th $83 to $398Professionalmedian $68 · 10th to 90th $55 to $288
$50$100$200$500facility $209professional $68

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$131.83
Median
$275.42
Typical High
$398.11
Aetna
Setting
Professional
Modifier
Global
Typical Low
$60.26
Median
$67.61
Typical High
$288.40
BCBS
Setting
Facility
Modifier
Global
Typical Low
$63.10
Median
$257.04
Typical High
$478.63
BCBS
Setting
Professional
Modifier
Global
Typical Low
$87.10
Median
$91.20
Typical High
$630.96
Cigna
Setting
Facility
Modifier
Global
Typical Low
$50.12
Median
$89.13
Typical High
$295.12
Cigna
Setting
Professional
Modifier
Global
Typical Low
$41.69
Median
$83.18
Typical High
$173.78
Medica
Setting
Facility
Modifier
Global
Typical Low
$70.79
Median
$100.00
Typical High
$229.09
Medica
Setting
Professional
Modifier
Global
Typical Low
$38.90
Median
$52.48
Typical High
$457.09
United
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$91.20
Typical High
$112.20
United
Setting
Professional
Modifier
Global
Typical Low
$38.90
Median
$52.48
Typical High
$125.89

Where Arizona sits

The same service costs 3.1 times more in Nebraska than in Vermont. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Arizona· 49th of 51

$74.13

NE $204VT $66.07

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.