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JAK2 V617F Gene Change Test

Alabama rates for HCPCS 81270

Looks in a blood or bone-marrow sample for one specific change in the JAK2 gene, known as V617F, which drives the marrow to overproduce blood cells. Finding it supports the diagnosis of a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia or myelofibrosis. The change is picked up during life in the blood-forming cells rather than inherited.

Rates data updated July 2026.

Facilitymedian $91 · 10th–90th $63$1740%10%20%10th90th$91Professionalmedian $76 · 10th–90th $55$1050%20%10th90th$76$50.0$100.0$200.0$500.0$1.0K$2.0K$5.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$91.20
Median
$104.71
Typical High
$263.03
Aetna
Setting
Professional
Modifier
Global
Typical Low
$54.95
Median
$75.86
Typical High
$104.71
BCBS
Setting
Facility
Modifier
Global
Typical Low
$58.88
Median
$70.79
Typical High
$95.50
BCBS
Setting
Professional
Modifier
Global
Typical Low
$63.10
Median
$77.62
Typical High
$120.23
Cigna
Setting
Facility
Modifier
Global
Typical Low
$72.44
Median
$79.43
Typical High
$288.40
Cigna
Setting
Professional
Modifier
Global
Typical Low
$40.74
Median
$54.95
Typical High
$524.81
United
Setting
Facility
Modifier
Global
Typical Low
$52.48
Median
$83.18
Typical High
$112.20
United
Setting
Professional
Modifier
Global
Typical Low
$38.90
Median
$52.48
Typical High
$125.89